Hospitalization rates and utilization among patients with rheumatoid arthritis: a population-based study from 1987 to 2012 in Olmsted County, Minnesota.
Hospitalization rates and utilization among patients with rheumatoid arthritis: a population-based study from 1987 to 2012 in Olmsted County, Minnesota.
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DOI：
10.1016/j.mayocp.2014.12.009
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发表时间：
2015-02
影响因子：
8.9
通讯作者：
Matteson EL
中科院分区：
文献类型：
--
作者：
Michet CJ 3rd;Strobova K;Achenbach S;Crowson CS;Matteson EL
研究类风湿关节炎（RA）患者的全因住院率是否与非RA患者不同。这是一项以明尼苏达州奥姆斯特德县为重点的回顾性、基于人群的队列研究。RA队列由1980-2007年首次符合1987年ACR RA标准的≥18岁患者组成，并与年龄、性别和日历年相似的非RA患者队列进行比较。以电子方式检索了1987-2012年的所有住院数据。分析采用人-年方法和率比（RR）比较RA患者和非RA患者。799例RA患者住院2968次，797例非RA患者住院2069次。RA患者的住院率高于非RA患者（RR 1.51，95%置信区间[CI] 1.42，1.59）。在研究的所有日历年和整个病程中，男女、所有年龄组的住院率都有所增加。男性类风湿关节炎患者因抑郁症住院的比率高于非类风湿关节炎男性受试者（RR 7.16，CI 2.78，30.67）。RA患者因糖尿病住院的比例高于非RA患者（RR 2.45，CI 1.34，4.89）。在RA中，疾病严重程度的指标（例如，血清阳性、糜烂、结节）与较高的住院率相关。RA患者因各种原因住院的比率高于非RA患者。住院率增加是真实的几种疾病类别和患者亚组。
To examine whether all-cause hospitalization rates for patients with rheumatoid arthritis (RA) differ from patients without RA. This is a retrospective, population-based cohort study focused on Olmsted County, Minnesota. The RA cohort consisted of patients aged ≥18 years who first fulfilled 1987 ACR criteria for RA in 1980-2007, and was compared to a cohort of similar age, sex, and calendar year without RA. Data on all hospitalizations were retrieved electronically for 1987-2012. Analyses utilized person-year methods and rate ratios (RR) comparing patients with and without RA. The 799 patients with RA experienced 2968 hospitalizations and the 797 patients without RA experienced 2069 hospitalizations. Patients with RA were hospitalized at a greater rate than patients without RA (RR 1.51, 95% confidence interval [CI] 1.42, 1.59). This increased rate of hospitalization was found in both sexes, all age groups, all calendar years studied and throughout disease duration. Male patients with RA were hospitalized for depression at a greater rate than male subjects without RA (RR 7.16, CI 2.78, 30.67). Patients with RA were hospitalized at a greater rate for diabetes mellitus than subjects without RA (RR 2.45, CI 1.34, 4.89). Among the RA, the indicators of disease severity (e.g., seropositivity, erosions, nodules) in the first year following RA incidence were associated with higher rates of hospitalization. Patients with RA were hospitalized for all causes at a greater rate than patients without RA. Increased rates of hospitalization were true for several disease categories and patient sub-groups.
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影响因子：
--
作者：
Gabriel, SE;Crowson, CS;Matteson, EL
通讯作者：
Matteson, EL
影响因子：
8.9
作者：
St Sauver, Jennifer L.;Grossardt, Brandon R.;Rocca, Walter A.
通讯作者：
Rocca, Walter A.
影响因子：
5
作者：
St Sauver, Jennifer L.;Grossardt, Brandon R.;Rocca, Walter A.
通讯作者：
Rocca, Walter A.
影响因子：
--
作者：
Doran, MF;Crowson, CS;Gabriel, SE
通讯作者：
Gabriel, SE
影响因子：
27.4
作者：
Finckh, A.;Choi, H. K.;Wolfe, F.
通讯作者：
Wolfe, F.