Modeling the biomechanics of swine mastication--an inverse dynamics approach.
Modeling the biomechanics of swine mastication--an inverse dynamics approach.
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DOI：
10.1016/j.jbiomech.2014.05.019
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发表时间：
2014-08-22
影响因子：
2.4
通讯作者：
Armand, Mehran
中科院分区：
文献类型：
--
作者：
Basafa, Ehsan;Murphy, Ryan J.;Gordon, Chad R.;Armand, Mehran
针对严重面部结构畸形患者的一种新颖的重建替代方案是基于 Le Fort 的面颌牙齿移植 (FJTT)。然而，迄今为止，只有十次手术涉及底层骨骼和颌牙组件，由于尺寸不匹配和缺乏精确的计划，所有手术都产生了次优结果，并且需要进行后续修复手术。大量研究证明猪是转化研究的合适候选者，包括术前移植计划。规划 FJTT 的一个重要方面是确定接受者下颌上的最佳肌肉附着部位，这需要清楚地了解与新捐赠的上颌和/或下颌相关的咀嚼和咬合力学。分段 CT 扫描结合文献数据定义了猪下颌骨和下颌肌肉的生物力学模型。该模型使用先前发布的一个咀嚼周期的跟踪运动和外力数据来驱动，并预测肌肉激活模式以及颞下颌关节 (TMJ) 反作用力和髁突运动。使用多项式和最小/最大优化两种方法来解决肌肉募集问题。两种方法之间观察到相似的性能。平均而言，所有肌肉的预测激活水平和测量激活水平之间的平均绝对误差 (MAE) <0.08，TMJ 反作用力的 MAE <7N。模拟激活在质量上遵循与参考数据相同的模式，并且模拟 TMJ 力具有非常好的一致性。多项式优化产生了更平滑的输出，表明它更适合研究此类运动。髁突运动的平均 MAE 为 1.2 毫米，当输入切牙运动按比例缩放以反映当前猪模型和原始猪模型之间可能存在的尺寸不匹配时，MAE 减少至 0.37 毫米。结果支持该模型可用于面部移植规划的假设。
A novel reconstructive alternative for patients with severe facial structural deformity is Le Fort-based, face-jaw-teeth transplantation (FJTT). To date, however, only ten surgeries have included underlying skeletal and jaw-teeth components, all yielding sub-optimal results and a need for a subsequent revision surgery, due to size mismatch and lack of precise planning. Numerous studies have proven swine to be appropriate candidates for translational studies including pre-operative planning of transplantation. An important aspect of planning FJTT is determining the optimal muscle attachment sites on the recipient’s jaw, which requires a clear understanding of mastication and bite mechanics in relation to the new donated upper and/or lower jaw. A segmented CT scan coupled with data taken from literature defined a biomechanical model of mandible and jaw muscles of a swine. The model was driven using tracked motion and external force data of one cycle of chewing published earlier, and predicted the muscle activation patterns as well as temporomandibular joint (TMJ) reaction forces and condylar motions. Two methods, polynomial and min/max optimization, were used for solving the muscle recruitment problem. Similar performances were observed between the two methods. On average, there was a mean absolute error (MAE) of <0.08 between the predicted and measured activation levels of all muscles, and an MAE of <7N for TMJ reaction forces. Simulated activations qualitatively followed the same patterns as the reference data and there was very good agreement for simulated TMJ forces. The polynomial optimization produced a smoother output, suggesting that it is more suitable for studying such motions. Average MAE for condylar motion was 1.2mm, which reduced to 0.37mm when the input incisor motion was scaled to reflect the possible size mismatch between the current and original swine models. Results support the hypothesis that the model can be used for planning of facial transplantation.
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影响因子：
2.4
作者：
Langenbach, G. E. J.;Zhang, F.;Hannam, A. G.
通讯作者：
Hannam, A. G.
影响因子：
3
作者：
Langenbach, GEJ;Hannam, AG
通讯作者：
Hannam, AG
影响因子：
3.4
作者：
HERRING, SW;GRIMM, AF;GRIMM, BR
通讯作者：
GRIMM, BR
影响因子：
2.4
作者：
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通讯作者：
NAEIJE, M
影响因子：
4.2
作者：
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通讯作者：
de Zee, Mark