Moderate aortic stenosis: culprit or bystander?
Moderate aortic stenosis: culprit or bystander?
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DOI:
10.1136/openhrt-2021-001743
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发表时间:
2022-01
期刊:
影响因子:
2.7
通讯作者:
Strom JB
中科院分区:
文献类型:
--
作者:
Pankayatselvan V;Raber I;Playford D;Stewart S;Strange G;Strom JB
Non-rheumatic aortic stenosis (AS) is among the most common valvular diseases in the developed world. Current guidelines support aortic valve replacement (AVR) for severe symptomatic AS, which carries high morbidity and mortality when left untreated. In contrast, moderate AS has historically been thought to be a benign diagnosis for which the potential benefits of AVR are outweighed by the procedural risks. However, emerging data demonstrating the substantial mortality risk in untreated moderate AS and substantial improvements in periprocedural and perioperative mortality with AVR have challenged the traditional risk/benefit paradigm. As such, an appraisal of the contemporary data on morbidity and mortality associated with moderate AS and appropriate timing of valvular intervention in AS is warranted. In this review, we discuss the current understanding of moderate AS, including the epidemiology, current surveillance and management guidelines, clinical outcomes, and future studies.
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DOI:
10.1186/1532-429x-14-50
发表时间:
2012-07-28
期刊:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
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