Variation of interstitial glucose measurements assessed by continuous glucose monitors in healthy, nondiabetic individuals.

Variation of interstitial glucose measurements assessed by continuous glucose monitors in healthy, nondiabetic individuals.
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DOI:
10.2337/dc09-1971
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发表时间:
2010-06
期刊:
影响因子:
16.2
通讯作者:
Xing D
Xing D
中科院分区:
医学1区
文献类型:
--
作者:
Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group;Fox LA;Beck RW;Xing D

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使用连续血糖监测仪(CGM)对非糖尿病患者的日常生活中的血糖水平进行表征。74名年龄在9-65岁、糖耐量正常的健康儿童、青少年和成人使用盲目CGM设备3-7天。传感器葡萄糖浓度在一天中有91%的时间为71-120 mg/dl。感应值为≤60或>140 mg/dl的时间分别只有0.2%和0.4%。儿童的传感器葡萄糖浓度略高于成人(P=0.009),夜间的血糖浓度略低于白天(95vs.99 mg/dl,P<0.001)。用CGM测量的血糖值≤60和>140 mg/dl在健康的非糖尿病个体中并不常见。随着时间的推移,CGM可能有助于评估非糖尿病患者的糖耐量。此外,这些数据为使用CGM评估糖尿病受试者血糖控制的研究提供了比较的基础。
To characterize glucose levels during daily living using continuous glucose monitors (CGMs) in nondiabetic individuals. Seventy-four healthy children, adolescents, and adults aged 9–65 years with normal glucose tolerance used a blinded CGM device for 3 to 7 days. Sensor glucose concentrations were 71–120 mg/dl for 91% of the day. Sensor values were ≤60 or >140 mg/dl for only 0.2% and 0.4% of the day, respectively. Sensor glucose concentrations were slightly higher in children than adults (P = 0.009) and were slightly lower during the night than day (95 vs. 99 mg/dl, P < 0.001). Glucose values ≤60 and >140 mg/dl, measured with CGM, are uncommon in healthy, nondiabetic individuals. CGM may be useful to evaluate glucose tolerance in nondiabetic individuals over time. Furthermore, these data provide a basis for comparison for studies that use CGM to assess glucose control in subjects with diabetes.
DOI: 10.2337/dc09-0076
发表时间: 2009-07
期刊: Diabetes care
影响因子: 16.2
作者:
Zhou J;Li H;Ran X;Yang W;Li Q;Peng Y;Li Y;Gao X;Luan X;Wang W;Jia W
通讯作者: Jia W