Reference values for continuous glucose monitoring in Chinese subjects.
Reference values for continuous glucose monitoring in Chinese subjects.
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DOI：
10.2337/dc09-0076
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发表时间：
2009-07
期刊：
影响因子：
16.2
通讯作者：
Jia W
中科院分区：
文献类型：
--
作者：
Zhou J;Li H;Ran X;Yang W;Li Q;Peng Y;Li Y;Gao X;Luan X;Wang W;Jia W
由于缺乏普遍接受的参考值，连续血糖监测（CGM）的广泛临床应用受到限制。本研究旨在建立中国健康受试者CGM参数的初步正常参考值。共有434名血糖调节正常的健康个体使用CGM系统完成了为期3天的血糖监测。分析24 h平均血糖（24 h MBG）和24 h内血糖水平≥140 mg/dl （PT140）和≤70 mg/dl （PT70）的时间百分比。手指棒血糖值与受试者CGM测量值具有良好的符合性。在434名受试者中，每日血糖从76.9±11.3到144.2±23.2 mg/dl不等。24h MBG、PT140和PT70分别为104±10 mg/dl、4.1±5.8%和2.4±5.3%。在这些参数上，男女之间没有明显差异。采用第95个百分位值作为CGM参数的上限，24 h MBG为119 mg/dl (6.6 mmol/l)， PT140为17.1%，PT70为11.7%。我们推荐24小时MBG值< 119mg /dl, PT140 <17%（4小时），PT70 <12%（3小时）作为中国人群的正常范围。
The widespread clinical application of continuous glucose monitoring (CGM) is limited by the lack of generally accepted reference values. This multicenter study aims to establish preliminary normal reference values for CGM parameters in a sample of healthy Chinese subjects. A total of 434 healthy individuals with normal glucose regulation completed a 3-day period of glucose monitoring using a CGM system. The 24-h mean blood glucose (24-h MBG) and the percentage of time that subjects' blood glucose levels were ≥140 mg/dl (PT140) and ≤70 mg/dl (PT70) within 24 h were analyzed. There was excellent compliance of finger stick blood glucose values with CGM measurements for subjects. Among the 434 subjects, the daily blood glucose varied from 76.9 ± 11.3 to 144.2 ± 23.2 mg/dl. The 24-h MBG, PT140, and PT70 were 104 ± 10 mg/dl, 4.1 ± 5.8%, and 2.4 ± 5.3%, respectively. As for these parameters, no significant differences were found between men and women. The 95th percentile values were adopted as the upper limits of CGM parameters, which revealed 119 mg/dl (6.6 mmol/l) for 24-h MBG, 17.1% for PT140, and 11.7% for PT70. We recommend a 24-h MBG value <119 mg/dl, PT140 <17% (4 h), and PT70 <12% (3 h) as normal ranges for the Chinese population.
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影响因子：
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