Long-term Management of Low Back Pain with Opioids and Non-steroidal Anti-inflammatory Drugs in a Health System.
Long-term Management of Low Back Pain with Opioids and Non-steroidal Anti-inflammatory Drugs in a Health System.
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在卫生系统中使用阿片类药物和非甾体抗炎药长期治疗腰痛。
DOI：
10.1016/j.amepre.2016.02.001
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发表时间：
2016
影响因子：
5.5
通讯作者：
Williams,LKeoki
中科院分区：
文献类型：
--
作者：
Ahmedani,BrianK;Peterson,EdwardL;Wells,KarenE;Henein,Fady;Williams,LKeoki
MethodsThe IRB of Henry Ford Hospital approved this study, which included 3,747 individuals who were health system members between 1998 and 2012. All individuals were aged≥ 18 years, had an incident lumbago diagnosis (low back pain; ICD-9 code, 724.2), and filled a de novo prescription for an opioid or NSAID within 2 weeks of diagnosis. All individuals were required to be enrolled (with available records) for at least 6 months before the diagnosis and 12 months after the initial prescription. TheseResultsThe sample included de novo users of opioids (n= 387) and NSAIDs (n= 3,360). Overall, 8.5% of opioid initiates continued use for 1 year as compared with 2.1% of NSAID initiates (Table 1). Among those who stopped and restarted, 7.9% of opioid users subsequently continued use for 1 year versus 4.4% of NSAID users. Continuous use was more common among opioid users (AOR= 3.06, p< 0.001). Opioid users were also more likely to use continuously after restarting when compared with NSAID users (OR= 1.87, p=DiscussionThis study presents information on the long-term use of opioids and NSAIDs for non-cancer low back pain. The data indicate that long-term use in this sample is three times more likely among opioid as compared with NSAID initiates. These data are important, given evidence that chronic use of opioids may lead to addiction and hyperalgesia—possible reasons for long-term use among opioids initiates. 2, 10 Alternatively, opioids may have been used long term if improved symptoms were observed. 4, 7, 9
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DOI：
10.1016/j.jpain.2008.10.008
发表时间：
2009-02
期刊：
The journal of pain
影响因子：
--
作者：
Chou R;Fanciullo GJ;Fine PG;Adler JA;Ballantyne JC;Davies P;Donovan MI;Fishbain DA;Foley KM;Fudin J;Gilson AM;Kelter A;Mauskop A;O'Connor PG;Passik SD;Pasternak GW;Portenoy RK;Rich BA;Roberts RG;Todd KH;Miaskowski C;American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
通讯作者：
American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
开阿片类药物治疗受伤工人疼痛的指南。
影响因子：
1.7
作者：
Jaymie Mai;G. Franklin;D. Tauben
通讯作者：
D. Tauben
影响因子：
2.7
作者：
Kuritzky L;Samraj GP
通讯作者：
Samraj GP
影响因子：
120.7
作者：
Makris, Una E.;Abrams, Robert C.;Gurland, Barry;Reid, M. Carrington
通讯作者：
Reid, M. Carrington
生命体征：处方阿片类止痛药过量——美国，1999--2008。
DOI：
--
发表时间：
2011
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
L. Paulozzi;Christopher M. Jones;K. Mack;R. A. Rudd
通讯作者：
R. A. Rudd