Sources and Biomarkers of Secondhand Tobacco Smoke Exposure in Urban Adolescents.
Sources and Biomarkers of Secondhand Tobacco Smoke Exposure in Urban Adolescents.
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DOI：
10.1016/j.acap.2019.12.006
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发表时间：
2020-05
影响因子：
3.1
通讯作者：
Benowitz NL
中科院分区：
文献类型：
--
作者：
Nardone N;Jain S;Addo N;St Helen G;Jacob P 3rd;Benowitz NL
在城市青少年人群中，我们评估了二手烟暴露（SHS）的暴露来源，检查了种族/民族，年龄和性别的暴露差异，并确定了暴露来源与生物标志物可替宁和NNAL之间的关系。参与者从美国加利福尼亚州旧金山弗朗西斯科的一家公立医院门诊招募。在筛选的N = 298名青少年样本中，235名被生物学证实暴露于烟草烟雾。其中，N = 16例为主动吸烟者，N = 219例暴露于SHS; 91例（39%）重度SHS暴露（中位可替宁= 0.76 ng/mL），128例（54%）轻度SHS暴露（中位可替宁= 0.11 ng/mL）。在这些SHS暴露中，最常见的暴露源是在公共场所。没有发现显着的种族/民族差异，虽然非洲裔美国青少年更有可能生活在一个家庭，允许吸烟。年龄较大的青少年更有可能通过几种不同的来源接触，女性更有可能在汽车和公共场所接触。过去7天在家中、汽车中的暴露和当前的钝性使用与暴露的生物标志物显著相关。城市青少年暴露于各种来源的SHS。虽然在公共场所的暴露是最常见的，但在家中和汽车中的暴露会显著影响烟草生物标志物水平。减少接触的干预措施如果侧重于减少在家中和汽车中的接触，将对这一人群产生最大的影响。钝性使用史是烟草暴露的一个强有力的决定因素。
In an urban adolescent population, we evaluated sources of exposure to secondhand smoke exposure (SHS), examined differences in exposure by race/ethnicity, age and sex, and determined the relationship between exposure source (s) and the biomarkers cotinine and NNAL. Participants were recruited from a public hospital-based outpatient clinic in San Francisco, CA, USA. Of a sample of N = 298 adolescents screened, 235 were biologically confirmed to be exposed to tobacco smoke. Of those, N = 16 were active smokers and N = 219 were exposed to SHS; 91 (39%) were heavily SHS exposed (median cotinine = 0.76 ng/mL) and 128 (54%) had light SHS exposure (median cotinine = 0.11 ng/mL). Within those SHS exposed, the most common source of exposure was in a public area. No significant racial/ethnic differences were found, although African American adolescents were more likely to live in a home that allowed smoking. Older adolescents were more likely to be exposed across several difference sources, and females more likely to be exposed in a car and in public areas. Past 7-day exposure in the home, in a car, and current blunt use were significantly related to biomarkers of exposure. Urban adolescents are exposed to SHS across a variety of sources. Although exposure in a public area is most common, exposure in the home and in cars significantly influences tobacco biomarker levels. Interventions to reduce exposure would have the greatest impact in this population if they focused on reducing exposure in the home and in cars. History of blunt use is a strong determinant of tobacco exposure.
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影响因子：
4.7
作者：
Benowitz, Neal L.;Jain, Shonul;Jacob, Peyton, III
通讯作者：
Jacob, Peyton, III
影响因子：
4.2
作者：
Peters, Erica N.;Schauer, Gillian L.;Pickworth, Wallace B.
通讯作者：
Pickworth, Wallace B.
影响因子：
7.4
作者：
Jacob, Peyton, III;Havel, Christopher;Benowitz, Neal L.
通讯作者：
Benowitz, Neal L.
DOI：
10.1016/j.jaip.2012.11.006
发表时间：
2013-03-01
影响因子：
9.4
作者：
Lang, Jason E.;Dozor, Allen J.;Lima, John J.
通讯作者：
Lima, John J.
影响因子：
4.7
作者：
Goniewicz, Maciej Lukasz;Eisner, Mark D.;Benowitz, Neal L.
通讯作者：
Benowitz, Neal L.