Induced pluripotent stem cells for regenerative medicine.
Induced pluripotent stem cells for regenerative medicine.
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DOI:
10.1146/annurev-bioeng-071813-105108
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发表时间:
2014-07-11
影响因子:
9.7
通讯作者:
Roy K
中科院分区:
文献类型:
--
作者:
Hirschi KK;Li S;Roy K
With the discovery of induced pluripotent stem (iPS) cells, it is now possible to convert differentiated somatic cells into multipotent stem cells that have the capacity to generate all cell types of adult tissues. Thus, there is a wide variety of applications for this technology, including regenerative medicine, in vitro disease modeling, and drug screening/discovery. Although biological and biochemical techniques have been well established for cell reprogramming, bioengineering technologies offer novel tools for the reprogramming, expansion, isolation, and differentiation of iPS cells. In this article, we review these bioengineering approaches for the derivation and manipulation of iPS cells and focus on their relevance to regenerative medicine.
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DOI:
10.1038/nrg3473
发表时间:
2013-06
期刊:
Nature reviews. Genetics
影响因子:
--
作者:
通讯作者:
--
DOI:
10.1007/978-1-62703-348-0_6
发表时间:
2013-01-01
期刊:
Methods in molecular biology (Clifton, N.J.)
影响因子:
--
作者:
Fontes, Andrew;Macarthur, Chad C;Vemuri, Mohan C
通讯作者:
Vemuri, Mohan C
影响因子:
4.1
作者:
Fridley, Krista M.;Fernandez, Irina;Roy, Krishnendu
通讯作者:
Roy, Krishnendu
影响因子:
48
作者:
Fluri DA;Tonge PD;Song H;Baptista RP;Shakiba N;Shukla S;Clarke G;Nagy A;Zandstra PW
通讯作者:
Zandstra PW
影响因子:
23.9
作者:
Ambasudhan R;Talantova M;Coleman R;Yuan X;Zhu S;Lipton SA;Ding S
通讯作者:
Ding S