Electromechanical relationship in hypertrophic cardiomyopathy.
Electromechanical relationship in hypertrophic cardiomyopathy.
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DOI：
10.1007/s12265-013-9481-0
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发表时间：
2013-08
影响因子：
3.4
通讯作者：
Abraham, M. Roselle
中科院分区：
文献类型：
--
作者：
Lin, Xiaoping;Liang, Hsin-Yueh;Pinheiro, Aurelio;Dimaano, Veronica;Sorensen, Lars;Aon, Miguel;Tereshchenko, Larisa G.;Chen, Yihan;Xiang, Meixiang;Abraham, Theodore P.;Abraham, M. Roselle
关键词：
我们研究了心电图复极异常与超声心动图变形异常之间是否存在关系。对128例临床诊断为肥厚性心肌病（HCM）的患者进行基线心电图和力学（回声变形）变化分析。与心电图正常的患者相比，左心室肥厚（LVH）或复极异常患者的间隔厚度更高。心电图显示LVH或QTc延长的患者收缩速度、收缩应变、收缩应变率、舒张后期速度和舒张后期应变率均低于心电图正常的患者。与心电图正常的患者相比，有应变型或ST段压降/ t波倒置的患者收缩速度、收缩应变、收缩应变率、舒张早期速度和舒张晚期速度均较低。心电表上LVH和复极化异常是HCM收缩和舒张力学受损的标志。
We examined whether there is a relationship between repolarization abnormalities on electrocardiography (EKG) and deformation abnormalities by echocardiography. Analysis of baseline EKGs and mechanical (echo-based deformation) changes was performed in 128 patients with a clinical diagnosis of hypertrophic cardiomyopathy (HCM). Patients with left ventricular hypertrophy (LVH) or repolarization abnormalities had higher septal thickness when compared to patients with normal EKG. Patients with EKG evidence of LVH or QTc prolongation had lower systolic velocity, systolic strain, systolic strain rate, late diastolic velocity, and late diastolic strain rate than patients with a normal EKG. Patients with strain pattern or ST depression/T-wave inversion had lower systolic velocity, systolic strain, systolic strain rate, early diastolic velocity, and late diastolic velocity when compared to patients with normal EKGs. LVH and repolarization abnormalities on surface EKG are markers of impaired systolic and diastolic mechanics in HCM.
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DOI：
10.1016/s0735-1097(00)01056-1
发表时间：
2001-01-01
影响因子：
24
作者：
Nagueh, SF;Sun, HB;Khoury, DS
通讯作者：
Khoury, DS
DOI：
10.1016/s0735-1097(01)01778-8
发表时间：
2002-02-20
影响因子：
24
作者：
Eriksson, MJ;Sonnenberg, B;Rakowski, H
通讯作者：
Rakowski, H
影响因子：
2.9
作者：
FLEMING, AD;MCDICKEN, WN;HOSKINS, PR
通讯作者：
HOSKINS, PR
影响因子：
39.3
作者：
Ganame, Javier;Mertens, Luc;Pignatelli, Ricardo H.
通讯作者：
Pignatelli, Ricardo H.
影响因子：
20.1
作者：
Ripplinger, Crystal M.;Li, Wenwen;Efimov, Igor R.
通讯作者：
Efimov, Igor R.