Obesity in cancer survival.
Obesity in cancer survival.
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癌症生存中的肥胖症。
DOI：
10.1146/annurev-nutr-071811-150713
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发表时间：
2012-08-21
影响因子：
8.9
通讯作者：
Bandera EV
中科院分区：
文献类型：
--
作者：
Parekh N;Chandran U;Bandera EV
虽然肥胖是几种癌症的一个众所周知的危险因素，但它在癌症存活中的作用却知之甚少。我们进行了一项系统的文献综述，以评估目前评估身体肥胖对三种最常见的肥胖相关癌症（前列腺癌、结直肠癌和乳腺癌）预后影响的证据。我们纳入了33项乳腺癌研究，6项前列腺癌研究，8项结直肠癌研究。我们注意到，这些证据过度代表了乳腺癌的生存研究，而前列腺癌和结直肠癌的证据却很少。总的来说，大多数研究支持身体肥胖与特定部位死亡率或癌症进展之间的关系。然而，大多数研究并不是专门为研究这些结果而设计的，因此，在整合这些结果以得出结论之前，应该考虑几个方法学问题。我们迫切需要进一步的研究来评估肥胖对不断增长的癌症幸存者群体的长期影响。
Although obesity is a well known risk factor for several cancers, its role on cancer survival is poorly understood. We conducted a systematic literature review to assess the current evidence evaluating the impact of body adiposity on the prognosis of the three most common obesity-related cancers: prostate, colorectal, and breast. We included 33 studies of breast cancer, six studies of prostate cancer, and eight studies of colorectal cancer. We note that the evidence over-represents breast cancer survivorship research and is sparse for prostate and colorectal cancers. Overall, most studies support a relationship between body adiposity and site-specific mortality or cancer progression. However, most of the research was not specifically designed to study these outcomes and, therefore, several methodological issues should be considered before integrating their results to draw conclusions. Further research is urgently warranted to assess the long-term impact of obesity among the growing population of cancer survivors.
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影响因子：
6.4
作者：
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通讯作者：
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影响因子：
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