In-depth proteomic profiling of the Singapore grouper iridovirus virion
In-depth proteomic profiling of the Singapore grouper iridovirus virion
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新加坡石斑鱼虹彩病毒病毒体的深入蛋白质组学分析
DOI:
10.1007/s00705-019-04264-3
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发表时间:
2019-05
影响因子:
2.7
通讯作者:
Lin Qingsong
中科院分区:
文献类型:
--
作者:
Yao Defu;Liu Yingfu;Chen Xiuli;Lim Teck Kwang;Wang Lili;Aweya Jude Juventus;Zhang Yueling;Lin Qingsong
Singapore grouper iridovirus (SGIV) is a lethal grouper virus containing 162 predicted ORFs. Previous proteomic studies led to identification of 73 SGIV structural proteins. Here, SDS-assisted tube-gel digestion and DOC-assisted in-solution digestion coupled with LC-ESI-MS/MS were applied to further profile the SGIV structural proteome. We identified a total of 90 SGIV structural proteins including 24 newly reported proteins. Additionally, several PTMs were identified, including 26 N-terminal acetylated proteins, three phosphorylated proteins, and one myristoylated protein. Importantly, 47 of the proteins that were identified are predicted to contain conserved domains. Our work greatly expands the repertoire of the SGIV structural proteome and provides more insight into the biology of SGIV.
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影响因子:
1.8
作者:
Wang J;Lee YM;Li C;Li P;Li Z;Lim TK;Gong Z;Lin Q
通讯作者:
Lin Q
影响因子:
4.6
作者:
Wang F;Liu Y;Zhu Y;Ngoc Tran B;Wu J;Leong Hew C
通讯作者:
Leong Hew C
影响因子:
3.4
作者:
Sheng Zhou;Qingjiao Wan;Youhua Huang;Xiaohong Huang;Jianhao Cao;Lili Ye;Teck-Kwang Lim;Qingsong Lin;Qiwei Qin
通讯作者:
Qiwei Qin
影响因子:
7
作者:
Wenjun Song;Q. Lin;S. Joshi;T. Lim;C. Hew
通讯作者:
Wenjun Song;Q. Lin;S. Joshi;T. Lim;C. Hew
影响因子:
3.8
作者:
Chen, Li Ming;Wang, Fan;Hew, Choy Leong
通讯作者:
Hew, Choy Leong