Signal activation and inactivation by the Gα helical domain: a long-neglected partner in G protein signaling.
Signal activation and inactivation by the Gα helical domain: a long-neglected partner in G protein signaling.
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DOI：
10.1126/scisignal.2003013
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发表时间：
2012-05-29
影响因子：
7.3
通讯作者：
Jones JC
中科院分区：
文献类型：
--
作者：
Dohlman HG;Jones JC
Heterotrimeric guanine nucleotide–binding proteins (G proteins) are positioned at the top of many signal transduction pathways. The G protein α subunit is composed of two domains, one that resembles Ras and another that is composed entirely of α helices. Historically, most attention has focused on the Ras-like domain, but emerging evidence reveals that the helical domain is an active participant in G protein signaling.
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DOI：
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