Cell signaling in space and time: where proteins come together and when they're apart.
Cell signaling in space and time: where proteins come together and when they're apart.
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时空信号传导:蛋白质聚集在一起以及它们分开的位置。
DOI:
10.1126/science.1175668
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发表时间:
2009-11-27
期刊:
影响因子:
--
通讯作者:
Pawson T
中科院分区:
文献类型:
--
作者:
Scott JD;Pawson T
Signal transduction can be defined as the coordinated relay of messages derived from extracellular cues to intracellular effectors. More simply put, information received on the cell surface is processed across the plasma membrane and transmitted to intracellular targets. This requires that the activators, effectors, enzymes, and substrates that respond to cellular signals come together when they need to.
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