Disorders of gut-brain interaction common among outpatients with eating disorders including avoidant/restrictive food intake disorder.
Disorders of gut-brain interaction common among outpatients with eating disorders including avoidant/restrictive food intake disorder.
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DOI：
10.1002/eat.23414
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发表时间：
2021-06
影响因子：
5.5
通讯作者：
Staller, Kyle
中科院分区：
文献类型：
--
作者：
Murray, Helen Burton;Kuo, Braden;Eddy, Kamryn T.;Breithaupt, Lauren;Becker, Kendra R.;Dreier, Melissa J.;Thomas, Jennifer J.;Staller, Kyle
关键词：
关于饮食失调（ED）门诊患者中的罗马IV肠脑相互作用障碍（DGBI;以前称为功能性胃肠道疾病）的研究很少。这些数据特别缺乏回避/限制性食物摄入障碍（ARFID），与DGBI共享核心特征。我们的目的是确定门诊ED患者DGBI症状的频率和性质。
2017年3月至2019年7月期间，在我们的三级护理艾德项目中诊断为艾德的连续转诊儿童和成人患者（n = 168，71%为女性，年龄8-76岁）完成了DGBI和精神病理学测量组合的改良罗马IV问卷。
大多数（n = 122，72%）参与者报告了至少一种令人烦恼的胃肠道症状。66例（39%）符合DBGI标准，最常见的是功能性消化不良-餐后窘迫综合征亚型（31%）。ARFID患者DGBI的发生率（30%）低于与体型或体重相关的ED（45%; X2[1] = 3.61，p = 0.058，Cramer's V = 0.147）。在ARFID患者中，DGBI的存在与厌恶后果原型和多个共病原型的存在相关。
我们证明了DGBI和ED之间的显著重叠，特别是餐后痛苦症状。需要进一步的研究来检查胃肠道症状是否是更大的艾德病理学的预测或结果，包括ARFID原型。
Little research exists on Rome IV disorders of gut–brain interaction (DGBI; formerly called functional gastrointestinal disorders) in outpatients with eating disorders (EDs). These data are particularly lacking for avoidant/restrictive food intake disorder (ARFID), which shares core features with DGBI. We aimed to identify the frequency and nature of DGBI symptoms among outpatients with EDs. Consecutively referred pediatric and adult patients diagnosed with an ED (n = 168, 71% female, ages 8–76 years) in our tertiary care ED program between March 2017 and July 2019 completed a modified Rome IV Questionnaire for DGBI and psychopathology measure battery. The majority (n = 122, 72%) of participants reported at least one bothersome gastrointestinal symptom. Sixty-six (39%) met criteria for a DBGI, most frequently functional dyspepsia—post-prandial distress syndrome subtype (31%). DGBI were surprisingly less frequent among patients with ARFID (30%) versus EDs that are associated with shape or weight concerns (45%; X2[1] = 3.61, p = .058, Cramer's V = .147). Among those with ARFID, DGBI presence was associated with the fear of aversive consequences prototype and multiple comorbid prototype presence. We demonstrated notable overlap between DGBI and EDs, particularly post-prandial distress symptoms. Further research is needed to examine if gastrointestinal symptoms predict or are a result of greater ED pathology, including ARFID prototypes.
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影响因子：
12.6
作者：
Murray, Helen Burton;Flanagan, Ryan;Staller, Kyle
通讯作者：
Staller, Kyle
影响因子：
12.6
作者：
Murray, Helen Burton;Bailey, Abbey P.;Kuo, Braden
通讯作者：
Kuo, Braden
影响因子：
5.9
作者：
Ljotsson, Brjann;Hesser, Hugo;Hedman, Erik
通讯作者：
Hedman, Erik
影响因子：
4.1
作者：
Bohn K;Doll HA;Cooper Z;O'Connor M;Palmer RL;Fairburn CG
通讯作者：
Fairburn CG
影响因子：
5.5
作者：
DeJong, Hannah;Perkins, Sarah;Schmidt, Ulrike
通讯作者：
Schmidt, Ulrike