A simple and soft chemical deaggregation method producing single-digit detonation nanodiamonds.
A simple and soft chemical deaggregation method producing single-digit detonation nanodiamonds.
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DOI：
10.1039/d1na00556a
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发表时间：
2022-05-17
影响因子：
4.7
通讯作者：
中科院分区：
文献类型：
--
作者：
爆轰纳米金刚石(DND)是一类非常小的球形金刚石纳米晶。它们被用于聚合物增强材料或纳米医学领域的药物输送系统。通过爆轰合成，只有最终解聚到个位数纳米尺寸(<；10 nm)才能充分发挥其潜力。现有的解聚方法主要依靠机械作用力，如大功率超声波破碎法或球磨法。这些技术带来的缺点是样品受到污染，需要专门的仪器。在这篇文章中，我们报道了一种纯粹的化学解聚方法，通过简单地结合空气中的氧化和沸腾的酸处理，在悬浮液中产生高度稳定的个位数的DNDS。得到的DND表面带有羧基，最后的沸腾酸处理去除了主要金属污染物，如镁、铁或铜，纳米颗粒保持分散在广泛的pH范围内。我们的方法可以很容易地在标准的化学实验室中进行，并有常用的实验设备。这是许多基于DND的应用的关键一步，从材料科学到生物或医疗应用。爆轰纳米金刚石(DND)是一类非常小的球形金刚石纳米晶。只有在解聚后，它们才能充分发挥其从聚合物增强材料到药物输送系统的多功能潜力。
Detonation nanodiamonds (DNDs) are a class of very small and spherical diamond nanocrystals. They are used in polymer reinforcement materials or as drug delivery systems in the field of nanomedicine. Synthesized by detonation, only the final deaggregation step down to the single-digit nanometer size (<10 nm) unfolds their full potential. Existing deaggregation methods mainly rely on mechanical forces, such as high-power sonication or bead milling. These techniques entail drawbacks such as contamination of the sample and the need for a specialized apparatus. In this paper, we report a purely chemical deaggregation method by simply combining oxidation in air followed by a boiling acid treatment, to produce highly stable single-digit DNDs in a suspension. The resulting DNDs are surface functionalized with carboxyl groups, the final boiling acid treatment removes primary metal contaminants such as magnesium, iron or copper and the nanoparticles remain dispersed over a wide pH range. Our method can be easily carried out in a standard chemistry laboratory with commonly available laboratory apparatus. This is a key step for many DND-based applications, ranging from materials science to biological or medical applications. Detonation nanodiamonds (DNDs) are a class of very small and spherical diamond nanocrystals. Only after deaggregation they fully unfold their versatile potential from polymer reinforcement materials to drug delivery systems.
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影响因子：
17.1
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