The Properties of Skin as a Diffusion Barrier and Route for Absorption
The Properties of Skin as a Diffusion Barrier and Route for Absorption
复制标题
皮肤作为扩散屏障和吸收途径的特性
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
P. Dugard
中科院分区：
文献类型：
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作者：
R. Scott;P. Dugard
哺乳动物的皮肤是一个复杂的综合器官。它是哺乳动物中最大的器官，成年男性的面积为18-22000平方厘米。基本上，它由最外层表皮、内层真皮以及相关的毛囊和汗管组成。我们对渗透性的主要兴趣是表皮，它负责皮肤最外层角质层的产生。据信，整个角质层构成渗透屏障，可能除了最外面的脱皮角质细胞（Kligman 1964）。
Mammalian skin is a complex, integrated organ. It is the largest organ in mammals and in an adult human male covers an area of 18–22000 cm2. Essentially, it is composed of the outermost epidermis, an inner dermis and associated hair follicles and sweat ducts. Our main interest in relation to the permeability properties is the epidermis which is responsible for the production of the outermost layer of the skin, the stratum corneum. The whole of the stratum corneum is believed to constitute the permeability barrier, with perhaps the exception of the outermost desquamating corneocytes (Kligman 1964).
影响因子：
6.5
作者：
SWARTZENDRUBER, DC;WERTZ, PW;DOWNING, DT
通讯作者：
DOWNING, DT
影响因子：
6.5
作者：
MADISON, KC;SWARTZENDRUBER, DC;DOWNING, DT
通讯作者：
DOWNING, DT