A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes.

A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes.
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DOI:
10.1039/c2cc17868k
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发表时间:
2012-04-28
期刊:
Chemical communications (Cambridge, England)
影响因子:
--
通讯作者:
Furdui CM
Furdui CM
中科院分区:
其他
文献类型:
--
作者:
Qian J;Wani R;Klomsiri C;Poole LB;Tsang AW;Furdui CM

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β-ketoesters are robust probes for labeling sulfenic acid (−SOH) proteins allowing quantitative cleavage of the tag for improved analysis of the labeled peptides by MS.
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