Mechanosensing in the immune response.
Mechanosensing in the immune response.
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DOI:
10.1016/j.semcdb.2017.08.031
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发表时间:
2017-11
影响因子:
7.3
通讯作者:
Upadhyaya A
中科院分区:
文献类型:
--
作者:
Upadhyaya A
Cells have a remarkable ability to sense and respond to the mechanical properties of their environment. Mechanosensing is essential for many phenomena from cell movements and tissue rearrangements to cell differentiation and the immune response. Cells of the immune system get activated when membrane receptors bind to cognate antigen on the surface of antigen presenting cells. Both T and B lymphocyte signaling has been shown to be responsive to physical forces and mechanical cues. Cytoskeletal forces exerted by cells likely mediate this mechanical modulation. Here we discuss recent advances in the field of immune cell mechanobiology at the molecular and cellular scale.
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影响因子:
3.4
作者:
DeMond, Andrew L.;Mossman, Kaspar D.;Groves, Jay T.
通讯作者:
Groves, Jay T.
DOI:
10.1083/jcb.201406120
发表时间:
2015-02-16
期刊:
The Journal of cell biology
影响因子:
--
作者:
Comrie WA;Li S;Boyle S;Burkhardt JK
通讯作者:
Burkhardt JK
DOI:
10.1083/jcb.201406121
发表时间:
2015-02-16
期刊:
The Journal of cell biology
影响因子:
--
作者:
Comrie WA;Babich A;Burkhardt JK
通讯作者:
Burkhardt JK
DOI:
10.1083/jcb.201201018
发表时间:
2012-06-11
期刊:
The Journal of cell biology
影响因子:
--
作者:
Babich A;Li S;O'Connor RS;Milone MC;Freedman BD;Burkhardt JK
通讯作者:
Burkhardt JK
影响因子:
30.5
作者:
Barda-Saad, M;Braiman, A;Samelson, LE
通讯作者:
Samelson, LE