Mechanosensing in the immune response.

Mechanosensing in the immune response.
复制标题

DOI:
10.1016/j.semcdb.2017.08.031
复制
发表时间:
2017-11
影响因子:
7.3
通讯作者:
Upadhyaya A
Upadhyaya A
中科院分区:
生物学2区
文献类型:
--
作者:
Upadhyaya A

文献摘要

参考文献

被引文献

相似文献

细胞具有非凡的感知和响应环境机械特性的能力。从细胞运动和组织重排到细胞分化和免疫反应,机械传感对许多现象都是必不可少的。当膜受体与抗原提呈细胞表面的同源抗原结合时,免疫系统的细胞就会被激活。T和B淋巴细胞信号都被证明对物理力量和机械信号有反应。细胞施加的细胞骨架力可能参与了这种机械调节。在这里,我们在分子和细胞水平上讨论免疫细胞机械生物学领域的最新进展。
Cells have a remarkable ability to sense and respond to the mechanical properties of their environment. Mechanosensing is essential for many phenomena from cell movements and tissue rearrangements to cell differentiation and the immune response. Cells of the immune system get activated when membrane receptors bind to cognate antigen on the surface of antigen presenting cells. Both T and B lymphocyte signaling has been shown to be responsive to physical forces and mechanical cues. Cytoskeletal forces exerted by cells likely mediate this mechanical modulation. Here we discuss recent advances in the field of immune cell mechanobiology at the molecular and cellular scale.
DOI: 10.1529/biophysj.107.119099
发表时间: 2008-04-15
影响因子: 3.4
作者:
DeMond, Andrew L.;Mossman, Kaspar D.;Groves, Jay T.
通讯作者: Groves, Jay T.
DOI: 10.1083/jcb.201406120
发表时间: 2015-02-16
期刊: The Journal of cell biology
影响因子: --
作者:
Comrie WA;Li S;Boyle S;Burkhardt JK
通讯作者: Burkhardt JK
DOI: 10.1083/jcb.201406121
发表时间: 2015-02-16
期刊: The Journal of cell biology
影响因子: --
作者:
Comrie WA;Babich A;Burkhardt JK
通讯作者: Burkhardt JK
DOI: 10.1083/jcb.201201018
发表时间: 2012-06-11
期刊: The Journal of cell biology
影响因子: --
作者:
Babich A;Li S;O'Connor RS;Milone MC;Freedman BD;Burkhardt JK
通讯作者: Burkhardt JK
DOI: 10.1038/ni1143
发表时间: 2005-01-01
期刊: NATURE IMMUNOLOGY
影响因子: 30.5
作者:
Barda-Saad, M;Braiman, A;Samelson, LE
通讯作者: Samelson, LE