The SpikerBox: a low cost, open-source bioamplifier for increasing public participation in neuroscience inquiry.

The SpikerBox: a low cost, open-source bioamplifier for increasing public participation in neuroscience inquiry.
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DOI:
10.1371/journal.pone.0030837
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Gage GJ
Gage GJ
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Marzullo TC;Gage GJ

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尽管人们普遍对大脑的功能感兴趣,但由于缺乏低成本和吸引人的教材,面向公众的神经科学教育受到了阻碍。为了解决这个问题,我们开发了一个开源工具,SpikerBox,它适用于初中/高中教育项目和业余爱好者。这种装置可以用于简单的实验,学生将缝纫针插入蟑螂或其他无脊椎动物的腿中,以放大和收听神经元的电活动。有了蟑螂腿的准备,学生们可以听到和看到(使用我们开发的智能手机示波器应用程序)触摸机械敏感倒刺引起的活动的巨大变化。学生们还可以尝试其他操作,如温度、药物和影响神经活动的微刺激。我们在补充材料中包括教学指南和其他资源。这些与SpikerBox的实践课程已被证明在教授基础神经科学方面是有效的。
Although people are generally interested in how the brain functions, neuroscience education for the public is hampered by a lack of low cost and engaging teaching materials. To address this, we developed an open-source tool, the SpikerBox, which is appropriate for use in middle/high school educational programs and by amateurs. This device can be used in easy experiments in which students insert sewing pins into the leg of a cockroach, or other invertebrate, to amplify and listen to the electrical activity of neurons. With the cockroach leg preparation, students can hear and see (using a smartphone oscilloscope app we have developed) the dramatic changes in activity caused by touching the mechanosensitive barbs. Students can also experiment with other manipulations such as temperature, drugs, and microstimulation that affect the neural activity. We include teaching guides and other resources in the supplemental materials. These hands-on lessons with the SpikerBox have proven to be effective in teaching basic neuroscience.
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