The association between maternal cortisol and depression during pregnancy, a systematic review.

The association between maternal cortisol and depression during pregnancy, a systematic review.
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DOI:
10.1007/s00737-017-0777-y
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发表时间:
2018-03
期刊:
Archives of women's mental health
影响因子:
--
通讯作者:
Williams MA
Williams MA
中科院分区:
其他
文献类型:
--
作者:
Orta OR;Gelaye B;Bain PA;Williams MA

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怀孕期间收集皮质醇的时间是报告母体皮质醇与怀孕期间抑郁症之间关联的研究中的一个重要因素。我们的目的是进一步研究在何种程度上报告的协会不同的研究,根据时间的母亲皮质醇收集在怀孕期间。2016年12月15日,使用PubMed/MEDLINE(美国国家医学图书馆)、EMBASE(Elsevier; 1974 -)、护理和相关健康文献累积索引(CINAHL,EBSCO)、PsycINFO(EBSCO)和Web of Science Core Collection(Thomson路透社)识别记录。使用以下纳入标准筛选独特的摘要:1)妊娠期间评估的母体皮质醇,2)妊娠期间使用筛选工具评估的产前抑郁症,3)关于母体皮质醇与产前抑郁症之间相关性的报告,4)提供妊娠期间皮质醇评估时间的信息,包括一天中的时间和妊娠,5)不是综述文章或病例研究。识别了1,375条记录,产生了826个独特摘要。29篇文章符合所有纳入标准。总的来说,大多数研究报告母体皮质醇和产前抑郁症之间没有关联(N=17),唾液和血液是最常见的报告基质。早晨、第二和第三孕期是妊娠期间最常见的采集时间。在报告相关性的研究中(N=12),孕中期和孕晚期皮质醇评估更一致地报告了相关性,并且在预期恢复期观察到皮质醇浓度升高。我们的审查增加了关于这一主题的现有文献,突出了差距和战略下一步。
Timing of cortisol collection during pregnancy is an important factor within studies reporting on the association between maternal cortisol and depression during pregnancy. Our objective was to further examine the extent to which reported associations differed across studies according to time of maternal cortisol collection during pregnancy. On December 15 2016, records were identified using PubMed/MEDLINE (National Library of Medicine), EMBASE (Elsevier; 1974 -), Cumulative Index to Nursing and Allied Health Literature (CINAHL, EBSCO), PsycINFO (EBSCO), and Web of Science Core Collection (Thomson Reuters). Unique abstracts were screened using the following inclusion criteria: 1) maternal cortisol assessed during pregnancy, 2) antepartum depression assessed during pregnancy using a screening instrument, 3) reports on the association between maternal cortisol and antepartum depression, 4) provides information on timing of cortisol assessment during pregnancy, including time of day and gestation, and 5) not a review article or a case study. 1,375 records were identified, resulting in 826 unique abstracts. Twenty-nine articles met all inclusion criteria. On balance, most studies reported no association between maternal cortisol and antepartum depression (N=17) and saliva and blood were the most common reported matrices. Morning and second and third trimesters were the most common times of collection during pregnancy. Among studies reporting an association (N=12), second and third trimester cortisol assessments more consistently reported an association and elevated cortisol concentrations were observed in expected recovery periods. Our review adds to the existing literature on the topic, highlighting gaps and strategic next steps.
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