Oxygen therapy in patients with retinal artery occlusion: A meta-analysis.
Oxygen therapy in patients with retinal artery occlusion: A meta-analysis.
复制标题
视网膜动脉闭塞患者的氧疗：一项荟萃分析
DOI：
10.1371/journal.pone.0202154
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Xu Y
中科院分区：
文献类型：
--
作者：
Wu X;Chen S;Li S;Zhang J;Luan D;Zhao S;Chu Z;Xu Y
背景氧疗已被广泛应用于RAO（视网膜动脉阻塞）患者;然而，有不一致的结果报告。方法检索PubMed、Web of Science、EMBASE、Medline（OvidSP）、科克伦、中国知网（CNKI）和万方数据库。主要终点为视力（VA），使用RevMan 5.3软件对结局进行统计学分析。结果7篇随机对照试验符合纳入标准。接受氧疗的患者视力改善的概率是未接受氧疗的对照组的5.61倍（OR = 5.61，95%CI，3.60-8.73，p < 0.01）。吸氧方法（卡方= 0.18，df = 1，p = 0.67）、联合治疗（卡方= 0.21，df = 1，p = 0.64）或RAO类型（卡方= 0.06，df = 1，p = 0.81）之间未观察到统计学显著差异。相反，100%氧气（卡方= 4.55，df = 1，p < 0.05）和高压氧（卡方= 4.55，df = 1，p < 0.05）显著改善RAO患者的VA。3个月内疗效较好（χ 2 = 5.76，df = 1，p < 0.05）。最有效的治疗时间超过9小时（卡方= 6.58，df = 1，p < 0.05）。结论氧疗对RAO患者VA有明显改善作用，尤其是100%高压氧治疗9 h以上的患者。
Background Oxygen therapy has been widely used for RAO (retinal artery occlusion) patients; however, inconsistent results have been reported. Methods PubMed, Web of Science, EMBASE, Medline (OvidSP), Cochrane, China National Knowledge Infrastructure (CNKI), and Wanfang Database were examined. The primary endpoint was visual acuity (VA), and RevMan software 5.3 was used to statistically analyze the outcomes. Results Seven randomized controlled trials (RCTs) met the inclusion criteria. Patients who received oxygen therapy exhibited probability of visual improvement about 5.61 times compared with the control group who did not receive oxygen therapy (OR = 5.61; 95% CI, 3.60–8.73; p < 0.01). No statistically significant difference was observed between oxygen inhalation methods (Chi2 = 0.18, df = 1, p = 0.67), combined therapy (Chi2 = 0.21, df = 1, p = 0.64), or RAO type (Chi2 = 0.06, df = 1, p = 0.81). Conversely, 100% oxygen (Chi2 = 4.55, df = 1, p < 0.05) and hyperbaric oxygen (Chi2 = 4.55, df = 1, p < 0.05) significantly improved VA in RAO patients. Better effect was showed in period within 3 months (Chi2 = 5.76, df = 1, p < 0.05). The most effective treatment length was over 9 hours (Chi2 = 6.58, df = 1, p < 0.05). Conclusion Oxygen therapy demonstrated beneficial effects in improving VA in RAO patients, particularly when patients were treated with 100% hyperbaric oxygen and for over 9 hours.
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影响因子：
6.1
作者：
Chen Yanyun;Wang Wenying;Lu Ning
通讯作者：
Lu Ning
DOI：
10.2176/nmccrj.cr.2015-0243
发表时间：
2016-07
期刊：
NMC case report journal
影响因子：
--
作者：
Elkordy AM;Sato K;Inoue Y;Mano Y;Matsumoto Y;Takahashi A;Tominaga T
通讯作者：
Tominaga T
影响因子：
13.7
作者：
Atebara, NH;Brown, GC;Cater, J
通讯作者：
Cater, J
影响因子：
4.4
作者：
Gaydar, Vera;Ezrachi, David;Goldenberg-Cohen, Nitza
通讯作者：
Goldenberg-Cohen, Nitza
影响因子：
2.1
作者：
Gokce, Gokcen;Metin, Suleyman;Ekinci, Metin
通讯作者：
Ekinci, Metin