Trends in neural tube defect prevalence, folic acid fortification, and vitamin supplement use.
Trends in neural tube defect prevalence, folic acid fortification, and vitamin supplement use.
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神经管缺陷患病率、叶酸强化和维生素补充剂使用的趋势。
DOI：
10.1053/sper.2002.34773
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发表时间：
2002
影响因子：
3.4
通讯作者：
J. Mulinare
中科院分区：
文献类型：
--
作者：
R. Olney;J. Mulinare
在这篇综述中，作者分析了过去三十年神经管缺陷 (NTD) 发生率的国际趋势。基于人口的数据源包括亚特兰大大都会先天缺陷计划和国家出生缺陷预防网络中的其他美国出生缺陷监测计划、国际出生缺陷监测系统信息交换所以及美国和加拿大的生命记录。为了分析维生素消费趋势，我们回顾了美国国家健康和营养检查调查以及多种维生素使用国际调查的数据。我们讨论了与大多数国家 NTD 比率历史性和持续下降相关的因素的作用。这些因素包括产前诊断的引入和利用的增加、育龄妇女使用多种维生素的建议，以及自强制食品强化以来人群血液叶酸水平的增加。我们还讨论了进一步预防 NTD 的研究需求。这是美国政府的工作。其使用没有任何限制。
In this review, the authors analyze international trends in rates of neural tube defects (NTDs) during the past three decades. Population-based data sources include the Metropolitan Atlanta Congenital Defects Program and other US birth defects surveillance programs in the National Birth Defects Prevention Network, the International Clearinghouse for Birth Defects Monitoring Systems, and US and Canadian vital records. To analyze trends in vitamin consumption, we review data from the US National Health and Nutrition Examination Surveys and international surveys of multivitamin use. We discuss the role of factors associated with historic and continuing declines in NTD rates in most countries. These factors include the introduction and increased utilization of prenatal diagnosis, recommendations for multivitamin use in women of childbearing age, and population-wide increases in blood folate levels that have occurred since food fortification was mandated. We also discuss research needs for further NTD prevention. This is a US government work. There are no restrictions on its use.
影响因子：
158.5
作者：
Jacques, PF;Selhub, J;Rosenberg, IH
通讯作者：
Rosenberg, IH