Subtypes of nonmedical prescription drug misuse.

Subtypes of nonmedical prescription drug misuse.
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DOI:
10.1016/j.drugalcdep.2009.01.007
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发表时间:
2009-06-01
影响因子:
4.2
通讯作者:
Teter, Christian J.
Teter, Christian J.
中科院分区:
医学2区
文献类型:
--
作者:
McCabe, Sean Esteban;Boyd, Carol J.;Teter, Christian J.

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该研究使用了三个特征(即,动机、给药途径和与酒精共摄入)的非医疗处方药滥用的四个独立类别(即,疼痛,镇静/焦虑,睡眠和兴奋剂药物)检查亚型和药物相关的问题。一项网络调查是由随机抽取的3,639名就读于美国中西部一所大型四年制大学的本科生自行进行的。自我治疗亚型的特点是动机与处方药的主要药物适应症一致,仅口服给药途径,不与酒精共摄入。休闲亚型的特点是娱乐的动机,口服或非口服途径,并共同摄入。混合亚型包括动机、途径和共同摄入的其他组合。在报告非医疗处方药滥用的人中,约13%被归类为娱乐亚型,39%为自我治疗亚型,48%为混合亚型。各亚型在性别、种族和处方药类别方面存在显著差异。大约50%的自我治疗以外的亚型患者药物滥用筛查呈阳性。自我治疗亚型中物质使用和滥用的几率通常低于其他亚型。研究结果表明,在检查非医疗处方药滥用时,应考虑亚型,特别是止痛药。
This study used three characteristics (i.e., motive, route of administration, and co-ingestion with alcohol) of nonmedical prescription drug misuse across four separate classes (i.e., pain, sedative/anxiety, sleeping and stimulant medications) to examine subtypes and drug related problems. A Web survey was self-administered by a randomly selected sample of 3,639 undergraduate students attending a large Midwestern 4-year U.S. university. Self-treatment subtypes were characterized by motives consistent with the prescription drug's pharmaceutical main indication, oral only routes of administration, and no co-ingestion with alcohol. Recreational subtypes were characterized by recreational motives, oral or non-oral routes, and co-ingestion. Mixed subtypes consisted of other combinations of motives, routes, and co-ingestion. Among those who reported nonmedical prescription drug misuse, approximately 13% were classified into the recreational subtype, while 39% were in the self-treatment subtype, and 48% were in the mixed subtype. There were significant differences in the subtypes in terms of gender, race and prescription drug class. Approximately 50% of those in subtypes other than self-treatment screened positive for drug abuse. The odds of substance use and abuse were generally lower among self-treatment subtypes than other subtypes. The findings indicate subtypes should be considered when examining nonmedical prescription drug misuse, especially for pain medication.
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