ECO, the Evidence & Conclusion Ontology: community standard for evidence information.

ECO, the Evidence & Conclusion Ontology: community standard for evidence information.
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DOI:
10.1093/nar/gky1036
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发表时间:
2019-01-08
影响因子:
14.9
通讯作者:
Chibucos MC
Chibucos MC
中科院分区:
生物学2区
文献类型:
--
作者:
Giglio M;Tauber R;Nadendla S;Munro J;Olley D;Ball S;Mitraka E;Schriml LM;Gaudet P;Hobbs ET;Erill I;Siegele DA;Hu JC;Mungall C;Chibucos MC

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证据和结论本体论(ECO)包含描述证据类型和断言方法的术语(类)。ECO术语用于生物合成过程中,以获取支持生物学断言的证据(例如,证据Z支持的基因产品X具有功能Y)。通过获取这些信息,可以跟踪注释出处、建立质量控制措施和查询证据。ECO包含1500多个术语,被许多领先的生物资源使用,包括基因本体论、UniProt和几个模式生物数据库。ECO正在根据生物配置社区的需求不断进行扩展和修订。该本体可从GitHub(https://github.com/evidenceontology/))或项目网站(http://evidenceontology.org/).)免费下载用户可以通过该项目的GitHub网站申请新的条款或对现有条款进行更改。ECO在CC0 1.0 Universal下发布到公共领域。
The Evidence and Conclusion Ontology (ECO) contains terms (classes) that describe types of evidence and assertion methods. ECO terms are used in the process of biocuration to capture the evidence that supports biological assertions (e.g. gene product X has function Y as supported by evidence Z). Capture of this information allows tracking of annotation provenance, establishment of quality control measures and query of evidence. ECO contains over 1500 terms and is in use by many leading biological resources including the Gene Ontology, UniProt and several model organism databases. ECO is continually being expanded and revised based on the needs of the biocuration community. The ontology is freely available for download from GitHub (https://github.com/evidenceontology/) or the project’s website (http://evidenceontology.org/). Users can request new terms or changes to existing terms through the project’s GitHub site. ECO is released into the public domain under CC0 1.0 Universal.
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