Prebiotic Wheat Bran Fractions Induce Specific Microbiota Changes.
Prebiotic Wheat Bran Fractions Induce Specific Microbiota Changes.
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益生物小麦麸皮级分会引起特定的微生物变化。
DOI：
10.3389/fmicb.2018.00031
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发表时间：
2018
影响因子：
5.2
通讯作者：
Raes J
中科院分区：
文献类型：
--
作者：
D'hoe K;Conterno L;Fava F;Falony G;Vieira-Silva S;Vermeiren J;Tuohy K;Raes J
麦麸纤维被认为对人体健康有益，因为它们对肠道微生物群的组成和活性有影响。在这里，我们通过使用糊粉、全麦麸、超细麦麸和可溶性麦麸（swb）作为碳源进行一系列粪浆厌氧发酵实验，评估了选定麦麸组分的益生元潜力。通过将基于扩增子的群落分析与荧光原位杂交（FISH）方法相结合，我们发现培养条件有利于变形杆菌（如埃希氏菌和Bilophila）的生长。这些影响在除了一个[全麦麸（twb）]发酵实验中都被抵消了。双歧杆菌的生长是在使用超细、可溶性和twb发酵后刺激的，在后两者中作为细菌负荷普遍增加的一部分。正如之前在人类膳食补充剂研究中观察到的那样，超细发酵和swb发酵都会导致双歧杆菌和嗜杆菌之间的权衡，这些研究着眼于菊粉型果聚糖对人类肠道微生物群的影响。粉粉粉选择性地刺激了杜鹃花和产丁酸盐的玫瑰花的生长。所有发酵实验均能提高产气量；只有在可溶性麸皮孵育后才观察到丁酸盐浓度的增加。我们的研究结果为糊粉粉作为一种补充性益生元选择性靶向结肠丁酸盐生产者的发展开辟了前景。
Wheat bran fibers are considered beneficial to human health through their impact on gut microbiota composition and activity. Here, we assessed the prebiotic potential of selected bran fractions by performing a series of fecal slurry anaerobic fermentation experiments using aleurone as well as total, ultrafine, and soluble wheat bran (swb) as carbon sources. By combining amplicon-based community profiling with a fluorescent in situ hybridization (FISH) approach, we found that incubation conditions favor the growth of Proteobacteria such as Escherichia and Bilophila. These effects were countered in all but one [total wheat bran (twb)] fermentation experiments. Growth of Bifidobacterium species was stimulated after fermentation using ultrafine, soluble, and twb, in the latter two as part of a general increase in bacterial load. Both ultrafine and swb fermentation resulted in a trade-off between Bifidobacterium and Bilophila, as previously observed in human dietary supplementation studies looking at the effect of inulin-type fructans on the human gut microbiota. Aleurone selectively stimulated growth of Dorea and butyrate-producing Roseburia. All fermentation experiments induced enhanced gas production; increased butyrate concentrations were only observed following soluble bran incubation. Our results open perspectives for the development of aleurone as a complementary prebiotic selectively targeting colon butyrate producers.
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DOI：
10.1007/s10482-007-9215-x
发表时间：
2008-05-01
影响因子：
2.6
作者：
da Silva, Sofia M.;Venceslau, Sofia S.;Pereira, Ines A. C.
通讯作者：
Pereira, Ines A. C.
影响因子：
5.2
作者：
De Preter, Vicky;Falony, Gwen;Verbeke, Kristin
通讯作者：
Verbeke, Kristin
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
56.9
作者：
Falony, Gwen;Joossens, Marie;Raes, Jeroen
通讯作者：
Raes, Jeroen
影响因子：
3.6
作者：
Cloetens, Lieselotte;Broekaert, Willem F.;Verbeke, Kristin
通讯作者：
Verbeke, Kristin