Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants.

Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants.
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miRNA 和 siRNA 在植物生物和非生物胁迫反应中的作用。

DOI:
10.1016/j.bbagrm.2011.05.001
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发表时间:
2012-02
影响因子:
4.7
通讯作者:
Zhu, Jianhua
Zhu, Jianhua
中科院分区:
生物学2区
文献类型:
--
作者:
Khraiwesh, Basel;Zhu, Jian-Kang;Zhu, Jianhua

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小的非编码RNA是植物和动物中控制各种生物过程的独特类别的调节RNA。在植物中,几类具有特定大小和特定功能的小RNA通过一系列途径进化。小RNA的主要类别包括microRNA(miRNAs)和小干扰RNA(siRNAs),它们在生物起源上不同。miRNA通过与反向互补序列结合来控制同源靶基因的表达,导致靶RNA的切割或翻译抑制。siRNA具有与miRNA相似的结构、功能和生物发生,但其来源于长双链RNA,并且通常可以在靶序列处指导DNA甲基化。小分子RNA除了在植物的生长发育和基因组完整性的维持中发挥重要作用外,也是植物逆境应答的重要组成部分。植物应对环境胁迫的一种方式是通过小RNA的活性来修饰它们的基因表达。因此,了解小RNA如何调节基因表达将使研究人员能够探索小RNA在生物和非生物胁迫反应中的作用。本文综述了植物小分子RNA在逆境适应中的调控作用。
Small, non-coding RNAs are a distinct class of regulatory RNAs in plants and animals that control a variety of biological processes. In plants, several classes of small RNAs with specific sizes and dedicated functions have evolved through a series of pathways. The major classes of small RNAs include microRNAs (miRNAs) and small interfering RNAs (siRNAs), which differ in their biogenesis. miRNAs control the expression of cognate target genes by binding to reverse complementary sequences, resulting in cleavage or translational inhibition of the target RNAs. siRNAs have a similar structure, function, and biogenesis as miRNAs but are derived from long double-stranded RNAs and can often direct DNA methylation at target sequences. Besides their roles in growth and development and maintenance of genome integrity, small RNAs are also important components in plant stress responses. One way in which plants respond to environmental stress is by modifying their gene expression through the activity of small RNAs. Thus, understanding how small RNAs regulate gene expression will enable researchers to explore the role of small RNAs in biotic and abiotic stress responses. This review focuses on the regulatory roles of plant small RNAs in the adaptive response to stresses.
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