Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis.
Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis.
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DOI：
10.1111/j.1582-4934.2007.00075.x
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发表时间：
2007-07
影响因子：
5.3
通讯作者：
Stan RV
中科院分区：
文献类型：
--
作者：
Stan RV
血管内皮排列在整个心血管系统中，执行一系列重要功能，包括控制微血管通透性、凝血炎症、血管张力以及在正常和疾病状态下通过血管发生和血管生成形成新血管。正常内皮由异质细胞群组成，这些细胞群根据其所在的血管床和血管树节段进行分化。主要特征之一是特定亚细胞结构的表达，例如质膜囊泡或小窝、跨内皮通道、囊泡细胞器、内皮袋和窗孔，它们的存在定义了几种内皮形态类型。较少探索的观察是此类结构在不同血管生成环境中的差异表达。本综述将重点关注正常内皮以及不同血管生成环境中这些特定内皮结构的组成、结构和功能的最新进展。
Vascular endothelium lines the entire cardiovascular system where performs a series of vital functions including the control of microvascular permeability, coagulation inflammation, vascular tone as well as the formation of new vessels via vasculogenesis and angiogenesis in normal and disease states. Normal endothelium consists of heterogeneous populations of cells differentiated according to the vascular bed and segment of the vascular tree where they occur. One of the cardinal features is the expression of specific subcellular structures such as plas-malemmal vesicles or caveolae, transendothelial channels, vesiculo-vacuolar organelles, endothelial pockets and fenestrae, whose presence define several endothelial morphological types. A less explored observation is the differential expression of such structures in diverse settings of angiogenesis. This review will focus on the latest developments on the components, structure and function of these specific endothelial structures in normal endothelium as well as in diverse settings of angiogenesis.
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影响因子：
7.8
作者：
CLEMENTI, F;PALADE, GE
通讯作者：
PALADE, GE
影响因子：
6
作者：
Baluk, P;Lee, CG;McDonald, DM
通讯作者：
McDonald, DM
影响因子：
11.5
作者：
Carson-Walter, EB;Hampton, J;Walter, KA
通讯作者：
Walter, KA
DOI：
10.1084/jem.180.3.1141
发表时间：
1994-09-01
期刊：
The Journal of experimental medicine
影响因子：
--
作者：
Detmar M;Brown LF;Claffey KP;Yeo KT;Kocher O;Jackman RW;Berse B;Dvorak HF
通讯作者：
Dvorak HF
影响因子：
3.1
作者：
BANKSTON, PW;MILICI, AJ
通讯作者：
MILICI, AJ