Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease
Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease
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通过小肽阻断 EphB2 和 ADDL 之间的相互作用可挽救阿尔茨海默病小鼠模型中受损的突触可塑性和记忆缺陷
DOI:
10.1523/jneurosci.1327-16.2016
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发表时间:
2016-11
影响因子:
5.3
通讯作者:
Gao Can
中科院分区:
文献类型:
--
作者:
Shi Xiao-Dong;Sun Kai;Hu Rui;Liu Xiao-Ya;Hu Qiu-Mei;Sun Xiao-Yu;Yao Bin;Sun Nan;Hao Jing-Ru;Wei Pan;Han Yuan;Gao Can
Soluble amyloid-β (Aβ) oligomers, also known as Aβ-derived diffusible ligands (ADDLs), are thought to be the key pathogenic factor in Alzheimer's disease (AD), but there is still no effective treatment for preventing or reversing the progression of the di
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DOI:
10.1523/jneurosci.0203-11.2011
发表时间:
2011-05-04
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Li S;Jin M;Koeglsperger T;Shepardson NE;Shankar GM;Selkoe DJ
通讯作者:
Selkoe DJ
影响因子:
2.1
作者:
S. Mota;I. Ferreira;C. Pereira;C. Oliveira;A. Rego
通讯作者:
S. Mota;I. Ferreira;C. Pereira;C. Oliveira;A. Rego
影响因子:
64.8
作者:
S. Lesné;M. T. Koh;L. Kotilinek;R. Kayed;C. Glabe;A. Yang;M. Gallagher;K. Ashe
通讯作者:
S. Lesné;M. T. Koh;L. Kotilinek;R. Kayed;C. Glabe;A. Yang;M. Gallagher;K. Ashe
影响因子:
4.2
作者:
Lee, KW;Lee, SH;Han, PL
通讯作者:
Han, PL
影响因子:
64.5
作者:
Dalva, MB;Takasu, MA;Greenberg, ME
通讯作者:
Greenberg, ME