Replication and conjugative mobilization of broad host-range IncQ plasmids.
Replication and conjugative mobilization of broad host-range IncQ plasmids.
复制标题
广泛的宿主范围INCQ质粒的复制和共轭动员。
DOI:
10.1016/j.plasmid.2009.05.001
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发表时间:
2009-09
期刊:
影响因子:
2.6
通讯作者:
Meyer R
中科院分区:
文献类型:
--
作者:
Meyer R
The IncQ plasmids have a broader host-range than any other known replicating element in bacteria. Studies on the replication and conjugative mobilization of these plasmids, which have mostly been focused on the nearly identical RSF1010 and R1162, are summarized with a view to understanding how this broad host-range is achieved. Several significant features of IncQ plasmids emerge from these studies: (1) initiation of replication, involving DnaA-independent activation of the origin and a dedicated primase, is strictly host-independent. (2) The plasmids can be conjugatively mobilized by a variety of different type IV transporters, including those engaged in the secretion of proteins involved in pathogenesis. (3) Stability is insured by a combination of high copy-number and modulated gene expression to reduce metabolic load.
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影响因子:
4.9
作者:
Boenemann, Gabriele;Stiens, Michael;Schlueter, Andreas
通讯作者:
Schlueter, Andreas
影响因子:
3.5
作者:
BAGDASARIAN, M;LURZ, R;TIMMIS, KN
通讯作者:
TIMMIS, KN
影响因子:
3.2
作者:
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通讯作者:
Nester, EW
影响因子:
3.2
作者:
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通讯作者:
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影响因子:
3.2
作者:
DEGRAAFF, J;CROSA, JH;FALKOW, S
通讯作者:
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