Improvement of hemolytic anemia with GBT1118 is renoprotective in transgenic sickle mice.
Improvement of hemolytic anemia with GBT1118 is renoprotective in transgenic sickle mice.
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DOI:
10.1182/bloodadvances.2022007809
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发表时间:
2022-08-09
期刊:
影响因子:
7.5
通讯作者:
Saraf, Santosh L.
中科院分区:
文献类型:
--
作者:
Ren, Guohui;Setty, Suman;Zhang, Xu;Susma, Alexandru;Ruiz, Maria Armila;Minshall, Richard D.;Lash, James P.;Gordeuk, Victor R.;Saraf, Santosh L.
A reduction in hemolysis with voxelotor analog, GBT1118, reduced hemoglobinuria and kidney injury biomarkers in transgenic sickle mice. Improved chronic hemolysis preserved kidney function and histopathologic and ultrastructural changes in transgenic sickle mice.
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DOI:
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Acta physiologica (Oxford, England)
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