Role of B cells in maintaining helper T-cell memory.
Role of B cells in maintaining helper T-cell memory.
复制标题
B 细胞在维持辅助 T 细胞记忆中的作用。
DOI:
10.1098/rstb.2000.0572
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发表时间:
2000
期刊:
影响因子:
--
通讯作者:
D. Gray
中科院分区:
文献类型:
--
作者:
D. van Essen;P. Dullforce;D. Gray
The cellular interactions involved in maintaining CD4+ T-cell memory have hitherto not been identified. In this report, we have investigated the role played by B cells in this process. We show that that long-lasting helper T-cell memory depends on the presence of B cells, but that direct antigen presentation by B cells is not required. These findings provide new insights into the mechanisms which underlie helper T-cell memory. They also suggest that the efficacy of future vaccines will depend critically on the inclusion of B- as well as T-cell epitopes.
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DOI:
--
发表时间:
1993
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Kapasi,ZF;Burton,GF;Shultz,LD;Tew,JG;Szakal,AK
通讯作者:
Szakal,AK
影响因子:
4.4
作者:
David J. Topham;R. Tripp;A. Hamilton-Easton;S. Sarawar;P. Doherty
通讯作者:
David J. Topham;R. Tripp;A. Hamilton-Easton;S. Sarawar;P. Doherty
DOI:
--
发表时间:
1988
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Szakal,AK;Kosco,MH;Tew,JG
通讯作者:
Tew,JG
DOI:
--
发表时间:
1988
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Kosco,MH;Szakal,AK;Tew,JG
通讯作者:
Tew,JG
影响因子:
32.4
作者:
Zhang, XH;Sun, SQ;Sprent, J
通讯作者:
Sprent, J