Depression underdiagnosis and the effects on quality of life in outpatients with HIV at a Nigerian university teaching hospital

Depression underdiagnosis and the effects on quality of life in outpatients with HIV at a Nigerian university teaching hospital
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尼日利亚大学教学医院门诊艾滋病病毒感染者的抑郁症诊断不足及其对生活质量的影响

DOI:
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发表时间:
2011
期刊:
African journal of AIDS research : AJAR
影响因子:
--
通讯作者:
T. Sheikh
T. Sheikh
中科院分区:
--
文献类型:
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作者:
V. Olisah;O. Baiyewu;T. Sheikh

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这项研究的目的是确定抑郁症的频率在一个样本的艾滋病毒感染者和其水平的诊断不足,由主治医生。该研究还探讨了抑郁症对艾滋病毒感染者生活质量(QOL)的影响。在尼日利亚中部北方的艾哈迈杜·贝洛大学教学医院,对一家医疗门诊的艾滋病毒感染者进行了社会人口学调查问卷。采用流行病学研究中心抑郁量表(CES-D)筛查抑郁症状,采用神经精神病学临床评估量表(SCAN)确诊抑郁障碍。主治医生对患者的医疗记录进行了筛查,以记录抑郁症状或既往接受过抗抑郁药物治疗的情况。使用世界卫生组织生活质量评估简表(WHOQOL-BREF)测量生活质量的六个领域。共有310名HIV患者参与了这项研究;其中,14.2%(n = 44)符合抑郁症的诊断标准,根据国际疾病和相关健康问题统计分类第10版(ICD-10)。所有这些抑郁症病例以前都没有被任何主治医生发现。在310名参与者中,58名(18.7%)的总体生活质量评分为“差”,252名(81.3%)的总体生活质量评分为“平均或以上”。44例抑郁障碍患者中,28例(63.6%)为生活质量较差者。在所有其他领域观察到一个相当相似的模式,抑郁症患者占领域得分差的参与者的比例更大。因此,作者发现抑郁症在艾滋病毒感染者中很常见,但很少在临床上得到认可,并且与生活质量下降有关。识别和治疗艾滋病毒感染者的抑郁症将改善功能和总体健康状况。
The study aimed to determine the frequency of depressive disorder in a sample of patients with HIV and its level of underdiagnosis by attending physicians. The study also explored the effect of depressive disorder on the quality of life (QOL) of patients with HIV. A sociodemographic questionnaire was administered to patients with HIV attending a medical out-patient clinic at Ahmadu Bello University Teaching Hospital, central northern Nigeria. The Center for Epidemiologic Studies Depression Scale (CES-D) was used to screen for depressive symptoms, and the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) was used to confirm the diagnosis of depressive disorder. The patients’ medical records were screened for documentation of depressive symptoms or previous treatment with antidepressants by an attending physician. The World Health Organization Quality of Life assessment short version (WHOQOL-BREF) was used to measure six domains of QOL. A total of 310 patients with HIV participated in the study; of these, 14.2% (n = 44) met the diagnostic criteria for depressive disorder, according to the International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10). All of these cases of depressive disorder had not been previously recognised by any attending physician. Of the 310 participants, 58 (18.7%) had a ‘poor’ score and 252 (81.3%) had an ‘average or above’ score for overall QOL. Of the 44 with depressive disorder, 28 (63.6%) were among those with a poor score for overall QOL. A fairly similar pattern was observed for all the other domains, with patients with depressive disorder accounting for greater proportions of the participants with poor domain scores. Thus, the authors found that depression is common but seldom clinically recognised in people with HIV, and that it is associated with a reduction in quality of life. Identifying and treating depression in patients with HIV will improve functioning and general wellbeing.
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发表时间: 2001-05-01
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