Patient education integrated with acupuncture for relief of cancer-related fatigue randomized controlled feasibility study.
Patient education integrated with acupuncture for relief of cancer-related fatigue randomized controlled feasibility study.
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DOI：
10.1186/1472-6882-11-49
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发表时间：
2011-06-25
影响因子：
--
通讯作者：
Hui KK
中科院分区：
文献类型：
--
作者：
Johnston MF;Hays RD;Subramanian SK;Elashoff RM;Axe EK;Li JJ;Kim I;Vargas RB;Lee J;Yang L;Hui KK
癌症相关性疲乏（CRF）是一个突出的临床问题。有人呼吁采取多种方式的干预措施。我们在一项随机对照试验（RCT）中评估了将患者教育与针灸相结合以缓解CRF的可行性，该试验以乳腺癌幸存者为对照，使用常规护理。社会认知和整合医学理论指导整合患者教育与针灸到一个连贯的治疗方案。发言分两部分。首先，患者被教导通过优化运动常规，改善营养，实施一些额外的基于证据的认知行为技术来改善自我护理，例如每周四次50分钟的压力管理。第二，患者每周接受8次50分钟的针灸治疗。使用简明疲劳量表（BFI）评估预先规定的主要结局CRF。次要结局包括使用FACT-COGv 2评估的认知障碍的三个维度。由于招募困难，我们尝试了几种方法，从而制定了量身定制的招募策略：我们将肿瘤学家招募到核心研究团队中，并从肿瘤候诊室招募完成治疗的患者。与常规护理对照组相比，干预与BFI测量的疲劳下降2.38分相关（90%置信区间为0.586至5.014; p <0.10）。与认知功能障碍相关的结局无统计学意义。患者教育与针灸相结合具有非常有前途的效果，值得进行更大规模的RCT以确认结果。有效的征聘战略对于成功进行大规模审判至关重要。NCT00646633
Cancer-related fatigue (CRF) is a prominent clinical problem. There are calls for multi-modal interventions. We assessed the feasibility of delivering patient education integrated with acupuncture for relief of CRF in a pilot randomized controlled trial (RCT) with breast cancer survivors using usual care as control. Social cognitive and integrative medicine theories guided integration of patient education with acupuncture into a coherent treatment protocol. The intervention consisted of two parts. First, patients were taught to improve self-care by optimizing exercise routines, improving nutrition, implementing some additional evidence-based cognitive behavioral techniques such as stress management in four weekly 50-minute sessions. Second, patients received eight weekly 50-minute acupuncture sessions. The pre-specified primary outcome, CRF, was assessed with the Brief Fatigue Inventory (BFI). Secondary outcomes included three dimensions of cognitive impairment assessed with the FACT-COGv2. Due to difficulties in recruitment, we tried several methods that led to the development of a tailored recruitment strategy: we enlisted oncologists into the core research team and recruited patients completing treatment from oncology waiting rooms. Compared to usual care control, the intervention was associated with a 2.38-point decline in fatigue as measured by the BFI (90% Confidence Interval from 0.586 to 5.014; p <0.10). Outcomes associated with cognitive dysfunction were not statistically significant. Patient education integrated with acupuncture had a very promising effect that warrants conducting a larger RCT to confirm findings. An effective recruitment strategy will be essential for the successful execution of a larger-scale trial. NCT00646633
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影响因子：
--
作者：
Bell, IR;Caspi, O;Weil, A
通讯作者：
Weil, A
影响因子：
45.3
作者：
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通讯作者：
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影响因子：
3.8
作者：
Groenvold, Mogens;Petersen, Morten Aagaard;Mouridsen, Henning T.
通讯作者：
Mouridsen, Henning T.
影响因子：
4.7
作者：
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通讯作者：
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影响因子：
4.7
作者：
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通讯作者：
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