Contribution of cryptic epitopes in designing a group A streptococcal vaccine.
Contribution of cryptic epitopes in designing a group A streptococcal vaccine.
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DOI：
10.1080/21645515.2018.1462427
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发表时间：
2018
影响因子：
4.8
通讯作者：
Good MF
中科院分区：
文献类型：
--
作者：
Ozberk V;Pandey M;Good MF
A successful vaccine needs to target multiple strains of an organism. Streptococcus pyogenes is an organism that utilizes antigenic strain variation as a successful defence mechanism to circumvent the host immune response. Despite numerous efforts, there is currently no vaccine available for this organism. Here we review and discuss the significant obstacles to vaccine development, with a focus on how cryptic epitopes may provide a strategy to circumvent the obstacles of antigenic variation.
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影响因子：
5
作者：
Cunningham MW
通讯作者：
Cunningham MW
影响因子：
6.4
作者：
Batzloff, MR;Hayman, WA;Good, MF
通讯作者：
Good, MF
影响因子：
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作者：
Dale, James B.;Penfound, Thomas A.;Kotloff, Karen L.
通讯作者：
Kotloff, Karen L.
影响因子：
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作者：
Cleary, PP;Matsuka, YV;Olmsted, SB
通讯作者：
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作者：
Alam FM;Bateman C;Turner CE;Wiles S;Sriskandan S
通讯作者：
Sriskandan S