Characterization of magnetite nanoparticles for SQUID-relaxometry and magnetic needle biopsy.
Characterization of magnetite nanoparticles for SQUID-relaxometry and magnetic needle biopsy.
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DOI:
10.1016/j.jmmm.2009.02.067
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发表时间:
2009-05-01
影响因子:
2.7
通讯作者:
Flynn ER
中科院分区:
文献类型:
--
作者:
Adolphi NL;Huber DL;Jaetao JE;Bryant HC;Lovato DM;Fegan DL;Venturini EL;Monson TC;Tessier TE;Hathaway HJ;Bergemann C;Larson RS;Flynn ER
Magnetite nanoparticles (Chemicell SiMAG-TCL) were characterized by SQUID-relaxometry, susceptometry, and TEM. The magnetization detected by SQUID-relaxometry was 0.33% of that detected by susceptometry, indicating that the sensitivity of SQUID-relaxometry could be significantly increased through improved control of nanoparticle size. The relaxometry data were analyzed by the moment superposition model (MSM) to determine the distribution of nanoparticle moments. Analysis of the binding of CD34-conjugated nanoparticles to U937 leukemia cells revealed 60,000 nanoparticles per cell, which were collected from whole blood using a prototype magnetic biopsy needle, with a capture efficiency of >65% from a 750 µl sample volume in 1 minute.
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影响因子:
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通讯作者:
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DOI:
10.1073/pnas.97.26.14268
发表时间:
2000-12-19
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TANNER, BK