Subclass Distribution of Human Anti‐Staphylococcus aureus Alpha Toxin Antibodies: Suggestion of an IgG1, IgA1, IgG4 Switch Pattern

Subclass Distribution of Human Anti‐Staphylococcus aureus Alpha Toxin Antibodies: Suggestion of an IgG1, IgA1, IgG4 Switch Pattern
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人抗金黄色葡萄球菌 Alpha 毒素抗体的亚类分布:IgG1、IgA1、IgG4 转换模式的建议

DOI:
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发表时间:
1984
影响因子:
3.7
通讯作者:
C. I. Smith
C. I. Smith
中科院分区:
医学4区
文献类型:
--
作者:
L. Hammarström;M. Persson;C. I. Smith

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The subclass distribution of antibodies against alpha toxin from Staphylococcus aureus in man was investigated. Antibodies were restricted to IgG1, IgA1, and IgG4 and appeared to develop sequentially. These data suggest a distinct pattern of class and subclass switches in response to protein antigens. However, studies in immunodeficient (class‐ or subclass‐ deficient) donors show that the proposed patterns is not obligatory.
单个个体的单克隆 IgG、IgA 和 IgM 共享相同的独特型决定簇。
DOI: 10.1016/0161-5890(80)90100-5
发表时间: 1980
影响因子: 3.6
作者:
Krueger,RG;Knowlton,DR;Kyle,RA;Fair,DS
通讯作者: Fair,DS