Chemical waves in cell and developmental biology.
Chemical waves in cell and developmental biology.
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DOI:
10.1083/jcb.201701158
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发表时间:
2018-04-02
期刊:
影响因子:
--
通讯作者:
Di Talia S
中科院分区:
文献类型:
--
作者:
Deneke VE;Di Talia S
Deneke and Di Talia review how the spatiotemporal coordination of cellular functions across large distances is controlled by chemical waves. Many biological events, such as the propagation of nerve impulses, the synchronized cell cycles of early embryogenesis, and collective cell migration, must be coordinated with remarkable speed across very large distances. Such rapid coordination cannot be achieved by simple diffusion of molecules alone and requires specialized mechanisms. Although active transport can provide a directed and efficient way to travel across subcellular structures, it cannot account for the most rapid examples of coordination found in biology. Rather, these appear to be driven by mechanisms involving traveling waves of chemical activities that are able to propagate information rapidly across biological or physical systems. Indeed, recent advances in our ability to probe the dynamics of signaling pathways are revealing many examples of coordination of cellular and developmental processes through traveling chemical waves. Here, we will review the theoretical principles underlying such waves; highlight recent literature on their role in different contexts, ranging from chemotaxis to development; and discuss open questions and future perspectives on the study of chemical waves as an essential feature of cell and tissue physiology.
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影响因子:
16.6
作者:
Bischof J;Brand CA;Somogyi K;Májer I;Thome S;Mori M;Schwarz US;Lénárt P
通讯作者:
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作者:
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DOI:
10.1083/jcb.201211039
发表时间:
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期刊:
The Journal of cell biology
影响因子:
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作者:
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通讯作者:
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通讯作者:
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