Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals With Coronavirus Disease 2019.
Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals With Coronavirus Disease 2019.
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DOI:
10.1093/ofid/ofab153
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发表时间:
2021-08
影响因子:
4.2
通讯作者:
MGH COVID-19 Collection & Processing Teams
中科院分区:
文献类型:
--
作者:
Regan J;Flynn JP;Rosenthal A;Jordan H;Li Y;Chishti R;Giguel F;Corry H;Coxen K;Fajnzylber J;Gillespie E;Kuritzkes DR;Hacohen N;Goldberg MB;Filbin MR;Yu XG;Baden L;Ribeiro RM;Perelson AS;Conway JM;Li JZ;MGH COVID-19 Collection & Processing Teams
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms, whereas viremia peaked within 1 week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. Remdesivir treatment was associated with faster viral decay.
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DOI:
10.1056/nejmoa2029849
发表时间:
2021-01-21
期刊:
The New England journal of medicine
影响因子:
--
作者:
Chen P;Nirula A;Heller B;Gottlieb RL;Boscia J;Morris J;Huhn G;Cardona J;Mocherla B;Stosor V;Shawa I;Adams AC;Van Naarden J;Custer KL;Shen L;Durante M;Oakley G;Schade AE;Sabo J;Patel DR;Klekotka P;Skovronsky DM;BLAZE-1 Investigators
通讯作者:
BLAZE-1 Investigators
影响因子:
6.7
作者:
Zheng H;Li H;Guo L;Liang Y;Li J;Wang X;Hu Y;Wang L;Liao Y;Yang F;Li Y;Fan S;Li D;Cui P;Wang Q;Shi H;Chen Y;Yang Z;Yang J;Shen D;Cun W;Zhou X;Dong X;Wang Y;Chen Y;Dai Q;Jin W;He Z;Li Q;Liu L
通讯作者:
Liu L
影响因子:
82.9
作者:
He, Xi;Lau, Eric H. Y.;Leung, Gabriel M.
通讯作者:
Leung, Gabriel M.
影响因子:
6.7
作者:
Perelson AS;Ke R
通讯作者:
Ke R
影响因子:
158.5
作者:
Beigel, John H.;Tomashek, Kay M.;Lane, H. Clifford
通讯作者:
Lane, H. Clifford