The Intersection of Sleep Apnea and Severe Mental Illness in Veterans.

The Intersection of Sleep Apnea and Severe Mental Illness in Veterans.
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DOI:
10.1016/j.psym.2019.01.007
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发表时间:
2019-09
期刊:
影响因子:
3.4
通讯作者:
Bramoweth, Adam D.
Bramoweth, Adam D.
中科院分区:
医学4区
文献类型:
--
作者:
Soreca, Isabella;Tighe, Caitlan A.;Bramoweth, Adam D.

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患有严重精神疾病(SMI)的个体具有睡眠呼吸暂停的高患病率风险因素,但这些风险因素通常未被识别,部分原因是睡眠呼吸暂停、身体状况和症状之间的重叠(例如,肥胖,白天嗜睡),导致在高危人群中对睡眠呼吸暂停的潜在认识不足。本研究的目的是比较有和没有SMI的退伍军人的睡眠呼吸暂停患病率和临床特征。当前分析的数据来自2007日历年33,818名美国退伍军人的初级保健访问的管理数据集。医疗记录数据包括人口统计学特征,以及医疗,精神病和睡眠诊断。患有重度精神病的退伍军人睡眠呼吸暂停的患病率显著高于无重度精神病的退伍军人。年轻的退伍军人与SMI有较高的患病率睡眠呼吸暂停相对于老年退伍军人与SMI和退伍军人与SMI和睡眠呼吸暂停有更多的医疗合并症比退伍军人与SMI和无睡眠呼吸暂停。在大量的退伍军人样本中,患有SMI的人患睡眠呼吸暂停综合症的风险更大。此外,合并SMI和睡眠呼吸暂停的退伍军人合并医学疾病的风险更大。睡眠呼吸暂停似乎是一个关键的风险因素,增加发病率的退伍军人与SMI诊断,突出了治疗睡眠呼吸暂停的重要性,在一个具有挑战性的患者群体。
Individuals with serious mental illness (SMI) have a high prevalence of risk factors for sleep apnea, but these risk factors often go unrecognized, partly due to the overlap among sleep apnea, somatic conditions, and symptoms (e.g., obesity, daytime sleepiness), leading to potential under-recognition of sleep apnea in a high-risk population. The objective of our study was to compare sleep apnea prevalence and clinical features among Veterans with and without SMI. Data for the current analyses were drawn from an administrative dataset of 33,818 United States Military Veterans with a primary care visit in calendar year 2007. The medical record data included demographic characteristics, and medical, psychiatric, and sleep diagnoses. Veterans with SMI had a significantly higher prevalence of sleep apnea than those without SMI. Younger Veterans with SMI had a higher prevalence of sleep apnea relative to older Veterans with SMI and Veterans with SMI and sleep apnea had a greater number of medical comorbidities than Veterans with SMI and no sleep apnea. In a large sample of Veterans, those with SMI were at greater risk of having comorbid sleep apnea. Furthermore, Veterans with comorbid SMI and sleep apnea were at greater risk for increased rates of comorbid medical disorders. Sleep apnea appears to be a key risk factor for increased morbidity in Veterans with an SMI diagnosis, highlighting the importance of treating sleep apnea in a challenging patient population.
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