Pharmacological effects of the lipidosterolic extract of Serenoa repens (Permixon®) on rat prostate hyperplasia induced by hyperprolactinemia: Comparison with finasteride

Pharmacological effects of the lipidosterolic extract of Serenoa repens (Permixon®) on rat prostate hyperplasia induced by hyperprolactinemia: Comparison with finasteride
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锯棕榈脂质甾醇提取物(Permixon®)对高催乳素血症引起的大鼠前列腺增生的药理作用:与非那雄胺的比较

DOI:
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发表时间:
2000
期刊:
The Prostate
影响因子:
--
通讯作者:
N. Prevarskaya
N. Prevarskaya
中科院分区:
--
文献类型:
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作者:
F. van Coppenolle;X. Le Bourhis;Françoise Carpentier;Geoffrey Delaby;H. Cousse;J. Raynaud;J. Dupouy;N. Prevarskaya

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The growth of the prostate gland is mainly dependent on androgens. Other hormones, like prolactin (PRL), also influence prostate development. Our purpose was to analyze and compare the effects of two drugs (5α‐reductase inhibitor) used in the therapy of benign prostatic hyperplasia: lipidosterolic extract of Serenoa repens (LSESR), and finasteride in an in vivo model of rat prostate hyperplasia induced by hyperprolactinemia.
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