Abscopal but desirable: The contribution of immune responses to the efficacy of radiotherapy.

Abscopal but desirable: The contribution of immune responses to the efficacy of radiotherapy.
复制标题

DOI:
10.4161/onci.20074
复制
发表时间:
2012-07-01
期刊:
影响因子:
7.2
通讯作者:
Zitvogel L
Zitvogel L
中科院分区:
医学2区
文献类型:
--
作者:
Kroemer G;Zitvogel L

文献摘要

参考文献

被引文献

相似文献

放射疗法将电离辐射应用于身体的选定区域,具有破坏癌细胞的范围,作为治愈性疗法的一部分以去除原发性恶性肿瘤并防止手术后肿瘤复发,或者作为姑息性措施的一部分以避免骨和脑转移的局部进展。有趣的是,放射治疗不仅有局部效应,而且可能导致远处非放射性病变的延迟消退。最有可能的是,这些“远位”效应是由免疫系统介导的。
Radiotherapy applies ionizing irradiation to selected areas of the body with the scope of destroying cancer cells, either as part of curative therapies to remove a primary malignant tumor and to prevent tumor recurrence after surgery, or as part of palliative measures to avoid local advancement of bone and brain metastases. Intriguingly, radiotherapy does not only have local effects but may lead to the delayed regression of distant non-irradiated lesions. Most likely, these “abscopal” effects are mediated by the immune system.
DOI: 10.1158/1078-0432.ccr-09-0265
发表时间: 2009-09-01
期刊: Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子: --
作者:
Dewan MZ;Galloway AE;Kawashima N;Dewyngaert JK;Babb JS;Formenti SC;Demaria S
通讯作者: Demaria S
DOI: 10.1136/gut.43.4.575
发表时间: 1998-10-01
期刊: GUT
影响因子: 24.5
作者:
Ohba, K;Omagari, K;Kohno, S
通讯作者: Kohno, S
DOI: 10.1158/1078-0432.ccr-07-4485
发表时间: 2008-02-15
影响因子: 11.5
作者:
Shiraishi, Kenshiro;Ishiwata, Yoshiro;Kanegasaki, Shiro
通讯作者: Kanegasaki, Shiro
DOI: 10.1259/0007-1285-56-661-63
发表时间: 1983-01-01
影响因子: 2.6
作者:
REES, GJG;ROSS, CMD
通讯作者: ROSS, CMD
DOI: 10.1259/0007-1285-48-574-863
发表时间: 1975-01-01
影响因子: 2.6
作者:
KINGSLEY, DPE
通讯作者: KINGSLEY, DPE