Randomized Clinical Trial of an Internet-Based Adolescent Depression Prevention Intervention in Primary Care: Internalizing Symptom Outcomes.
Randomized Clinical Trial of an Internet-Based Adolescent Depression Prevention Intervention in Primary Care: Internalizing Symptom Outcomes.
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DOI：
10.3390/ijerph17217736
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发表时间：
2020-10-22
影响因子：
--
通讯作者：
Voorhees BWV
中科院分区：
文献类型：
--
作者：
Gladstone T;Buchholz KR;Fitzgibbon M;Schiffer L;Lee M;Voorhees BWV
大约20%的人在成年时会经历抑郁发作，这使得青春期成为预防的重要发展目标。CATCH-IT（有能力的成年过渡与认知行为，人文和人际关系培训），一种在线抑郁预防干预措施，已证明在预防青少年抑郁发作中的有效性。我们的研究探讨了CATCH-IT与在线健康教育（HE）对有抑郁风险的青少年内化症状的影响。年龄在13-18岁之间的参与者是从美国8个卫生系统招募的，并被随机分配到CATCH-IT或HE。在基线、2、6、12、18和24个月时完成评估。两组之间的抑郁症状（CATCH-IT组B =-0.31，HE组B =-0.27，p = 0.80）或焦虑（CATCH-IT组B =-0.13，HE组B =-0.11，p = 0.79）变化无显著差异。两组的抑郁症状改善具有统计学显著性（p < 0.05）（CATCH-IT组p = 0.004，HE组p = 0.009）;焦虑改善在CATCH-IT组有显著性（p = 0.04），但在HE组无显著性（p = 0.07）。父母抑郁和与初级保健医生（PRPC）的积极关系调节了焦虑的结果，青少年的外化症状和PRPC调节了抑郁的结果。这项研究证明了这两种在线程序对抑郁症状的长期积极影响，并表明CATCH-IT对焦虑也有交叉影响。
Approximately 20% of people will experience a depressive episode by adulthood, making adolescence an important developmental target for prevention. CATCH-IT (Competent Adulthood Transition with Cognitive-behavioral, Humanistic, and Interpersonal Training), an online depression prevention intervention, has demonstrated efficacy in preventing depressive episodes among adolescents reporting elevated symptoms. Our study examines the effects of CATCH-IT compared to online health education (HE) on internalizing symptoms in adolescents at risk for depression. Participants, ages 13–18, were recruited across eight US health systems and were randomly assigned to CATCH-IT or HE. Assessments were completed at baseline, 2, 6, 12, 18, and 24 months. There were no significant differences between groups in change in depressive symptoms (b = −0.31 for CATCH-IT, b = −0.27 for HE, p = 0.80) or anxiety (b = −0.13 for CATCH-IT, b = −0.11 for HE, p = 0.79). Improvement in depressive symptoms was statistically significant (p < 0.05) for both groups (p = 0.004 for CATCH-IT, p = 0.009 for HE); improvement in anxiety was significant for CATCH-IT (p = 0.04) but not HE (p = 0.07). Parental depression and positive relationships with primary care physicians (PRPC) moderated the anxiety findings, and adolescents’ externalizing symptoms and PRPC moderated the depression findings. This study demonstrates the long-term positive effects of both online programs on depressive symptoms and suggests that CATCH-IT demonstrates cross-over effects for anxiety as well.
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影响因子：
25.8
作者：
Beardslee, William R.;Brent, David A.;Weersing, V. Robin;Clarke, Gregory N.;Porta, Giovanna;Hollon, Steven D.;Gladstone, Tracy R. G.;Gallop, Robert;Lynch, Frances L.;Iyengar, Satish;DeBar, Lynn;Garber, Judy
通讯作者：
Garber, Judy
影响因子：
7.4
作者：
Garber, Judy;Brunwasser, Steven M.;Zerr, Argero A.;Schwartz, Karen T. G.;Sova, Karen;Weersing, V. Robin
通讯作者：
Weersing, V. Robin
预防阈下抑郁症成人的抑郁症：健康经济学评估以及基于网络干预的务实随机对照试验。
影响因子：
7.4
作者：
Buntrock C;Berking M;Smit F;Lehr D;Nobis S;Riper H;Cuijpers P;Ebert D
通讯作者：
Ebert D
影响因子：
25.8
作者：
Copeland WE;Wolke D;Shanahan L;Costello EJ
通讯作者：
Costello EJ
影响因子：
3.6
作者：
Eckshtain D;Marchette LK;Schleider J;Weisz JR
通讯作者：
Weisz JR