Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades.
Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades.
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DOI：
10.1186/1475-2875-10-131
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发表时间：
2011-05-18
期刊：
影响因子：
3
通讯作者：
von Seidlein L
中科院分区：
文献类型：
--
作者：
Andersen F;Douglas NM;Bustos D;Galappaththy G;Qi G;Hsiang MS;Kusriastuti R;Mendis K;Taleo G;Whittaker M;Price RN;von Seidlein L
已发表的疟疾研究缺乏量化数据。这项研究的目的是描述11个亚太国家1990年至2009年与疟疾有关的文献的趋势，这些国家致力于将消除疟疾作为国家目标。利用疟疾和11个目标国家(不丹、中国、朝鲜、印度尼西亚、马来西亚、菲律宾、所罗门群岛、韩国、斯里兰卡、泰国和瓦努阿图)对1990年1月至2009年12月发表在PubMed/MEDLINE上的文章进行系统检索。参考文献根据主题、疟原虫种类以及它们是否包含原始数据或衍生数据进行了整理和分类。1990至2009年间发表的2700篇文章涉及目标国家的疟疾。与疟疾有关的论文的年产量呈线性增长，而这些国家的总体生物医学产量则呈指数增长。1992年，与疟疾有关的出版物占所有生物医学出版物的比例接近3%，2009年降至不到1%(118/12171；p<；0.001)。与疟疾有关的论文绝对产量最高的是泰国(n=1211)，其次是中国(n=609)和印度尼西亚(n=346)。所罗门群岛和瓦努阿图的出版物绝对数量较少，但这两个国家的人均出版物数量最高(每千人1.3篇和2.5篇论文)。论文中涉及疟疾流行病学和控制的比例最高(53%)，其次是药物和耐药性研究(47%)。从第一个十年到第二个十年，与流行病学、昆虫学、生物学、分子生物学、病理生理学和诊断学有关的论文比例上升，而关于药物、疟疾临床方面、免疫学和社会科学的论文比例下降。在11个目标亚太国家的生物医学总产出中，与疟疾有关的出版物所占比例正在下降。发现和评估新的、安全有效的药物和疫苗至关重要。此外，消除疟疾将需要业务研究，以实施和扩大干预措施。
Quantitative data are lacking on published malaria research. The purpose of the study is to characterize trends in malaria-related literature from 1990 to 2009 in 11 Asian-Pacific countries that are committed to malaria elimination as a national goal. A systematic search was conducted for articles published from January 1990 to December 2009 in PubMed/MEDLINE using terms for malaria and 11 target countries (Bhutan, China, North Korea, Indonesia, Malaysia, Philippines, Solomon Islands, South Korea, Sri Lanka, Thailand and Vanuatu). The references were collated and categorized according to subject, Plasmodium species, and whether they contained original or derivative data. 2,700 articles published between 1990 and 2009 related to malaria in the target countries. The annual output of malaria-related papers increased linearly whereas the overall biomedical output from these countries grew exponentially. The percentage of malaria-related publications was nearly 3% (111/3741) of all biomedical publications in 1992 and decreased to less than 1% (118/12171; p < 0.001) in 2009. Thailand had the highest absolute output of malaria-related papers (n = 1211), followed by China (n = 609) and Indonesia (n = 346). Solomon Islands and Vanuatu had lower absolute numbers of publications, but both countries had the highest number of publications per capita (1.3 and 2.5 papers/1,000 population). The largest percentage of papers concerned the epidemiology and control of malaria (53%) followed by studies of drugs and drug resistance (47%). There was an increase in the proportion of articles relating to epidemiology, entomology, biology, molecular biology, pathophysiology and diagnostics from the first to the second decade, whereas the percentage of papers on drugs, clinical aspects of malaria, immunology, and social sciences decreased. The proportion of malaria-related publications out of the overall biomedical output from the 11 target Asian-Pacific countries is decreasing. The discovery and evaluation of new, safe and effective drugs and vaccines is paramount. In addition the elimination of malaria will require operational research to implement and scale up interventions.
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影响因子：
15.8
作者：
Snow, Robert W.;Guerra, Carlos A.;Hay, Simon I.
通讯作者：
Hay, Simon I.
影响因子：
3.5
作者：
Bharate, SB;Bhutani, KK;Singh, IP
通讯作者：
Singh, IP
影响因子：
15.8
作者：
Guerra, Carlos A.;Gikandi, Priscilla W.;Tatem, Andrew J.;Noor, Abdisalan M.;Smith, Dave L.;Hay, Simon I.;Snow, Robert W.
通讯作者：
Snow, Robert W.
影响因子：
3.8
作者：
Guerra CA;Howes RE;Patil AP;Gething PW;Van Boeckel TP;Temperley WH;Kabaria CW;Tatem AJ;Manh BH;Elyazar IR;Baird JK;Snow RW;Hay SI
通讯作者：
Hay SI
影响因子：
168.9
作者：
Feachem, Richard G. A.;Phillips, Allison A.;Hwang, Jimee;Cotter, Chris;Wielgosz, Benjamin;Greenwood, Brian M.;Sabot, Oliver;Henry Rodriguez, Mario;Abeyasinghe, Rabindra R.;Ghebreyesus, Tedros Adhanom;Snow, Robert W.
通讯作者：
Snow, Robert W.