Awareness and Acceptability of Undetectable = Untransmittable Among a U.S. National Sample of HIV-Negative Sexual and Gender Minorities.

Awareness and Acceptability of Undetectable = Untransmittable Among a U.S. National Sample of HIV-Negative Sexual and Gender Minorities.
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DOI:
10.1007/s10461-020-02990-3
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发表时间:
2021-03
期刊:
影响因子:
4.4
通讯作者:
Grov C
Grov C
中科院分区:
医学2区
文献类型:
--
作者:
Carneiro PB;Westmoreland DA;Patel VV;Grov C

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虽然“不可检测=不可传播”(U=U)的信息得到广泛认可,但对其广度和范围知之甚少。我们的研究描述了社会人口特征和性行为与听说和信任U=U在美国全国样本的艾滋病毒阴性参与者。数据来自Together 5,000队列研究,这是一项基于互联网的美国全国性队列研究,包括与男性发生性关系的顺式男性,跨式男性和跨式女性。在入组后约6个月,参与者完成了本横断面分析(n = 3286)中包含的可选调查。措施包括社会人口和医疗保健相关的特征;有关U=U(可靠变量)的知识和信任的问题。我们使用描述性统计和多变量logistic模型来识别与这些变量相关的特征,并探讨了无安全套肛交(CAS)意愿与信任U=U的模式。总体而言,85.5%的参与者表示听说过U=U。在那些知道U=U的人中,42.3%表示他们相信它,19.8%不相信,38.0%不确定。拉丁裔,亚洲,低收入和南方参与者不太可能听说过U=U。最近进行了关于PrEP的临床讨论或成为前PrEP用户与U=U的信任相关。参与CAS的意愿与对U=U的信任呈正相关,并且根据伴侣的血清状态,PrEP使用和病毒载量而变化。虽然我们发现意识的比例很高,不信任的程度很低,但我们的研究表明,主要社区仍然不知道和/或怀疑U=U。
While the “Undetectable=Untransmittable” (U=U) message is widely endorsed, little is known about its breadth and reach. Our study describes socio-demographic characteristics and sexual behaviors associated with having heard of and trusting in U=U in a U.S. national sample of HIV-negative participants. Data were derived from the Together 5,000 cohort study, an internet-based U.S. national cohort of cis men, trans men and trans women who have sex with men. Approximately 6 months after enrollment, participants completed an optional survey included in the present cross-sectional analysis (n = 3286). Measures included socio-demographic and healthcare-related characteristics; questions pertaining to knowledge of and trust in U=U (dependable variable). We used descriptive statistics and multivariable logistic models to identify characteristics associated with these variables and explored patterns in willingness to engage in condomless anal sex (CAS) with regard to trust in U=U. In total, 85.5% of participants reported having heard of U=U. Among those aware of U=U, 42.3% indicated they trusted it, 19.8% did not, and 38.0% were unsure about it. Latinx, Asian, lower income, and Southern participants were less likely to have heard of U=U. Having had a recent clinical discussion about PrEP or being a former-PrEP user were associated with trust in U=U. Willingness to engage in CAS was positively associated with trust in U=U, and varied based on the partner’s serostatus, PrEP use and viral load. Although we found high rates of awareness and low levels of distrust, our study indicated that key communities remain unaware and/or skeptical of U=U.
DOI: 10.1097/qad.0b013e3283324283
发表时间: 2010-01-02
期刊: AIDS (London, England)
影响因子: --
作者:
HIV-CAUSAL Collaboration;Ray M;Logan R;Sterne JA;Hernández-Díaz S;Robins JM;Sabin C;Bansi L;van Sighem A;de Wolf F;Costagliola D;Lanoy E;Bucher HC;von Wyl V;Esteve A;Casbona J;del Amo J;Moreno S;Justice A;Goulet J;Lodi S;Phillips A;Seng R;Meyer L;Pérez-Hoyos S;García de Olalla P;Hernán MA
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发表时间: 2012-07-01
影响因子: 12.7
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DOI: 10.1177/1545109711404946
发表时间: 2011-11
期刊: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)
影响因子: --
作者:
Sharma A;Sullivan PS;Khosropour CM
通讯作者: Khosropour CM
DOI: 10.1016/j.annepidem.2019.05.003
发表时间: 2019-07-01
影响因子: 5.6
作者:
Grov, Christian;Westmoreland, Drew A.;Nash, Denis
通讯作者: Nash, Denis