Lowering urinary oxalate excretion to decrease calcium oxalate stone disease.

Lowering urinary oxalate excretion to decrease calcium oxalate stone disease.
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DOI:
10.1007/s00240-015-0839-4
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发表时间:
2016-02
期刊:
影响因子:
3.1
通讯作者:
Assimos, Dean G.
Assimos, Dean G.
中科院分区:
医学2区
文献类型:
--
作者:
Holmes, Ross P.;Knight, John;Assimos, Dean G.

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饮食调整应被视为治疗特发性草酸钙肾结石的一线方法。饮食中消耗的草酸盐和钙的量是疾病发展的重要因素,因为它们影响尿草酸盐排泄。有许多策略可用于减少草酸盐排泄。应避免食用富含钙的食物,并将钙摄入量调整为1000-1200 mg/天。为了鼓励患者依从性,应向患者强调他们对这种饮食保持警惕,因为任何膳食或零食的偏差都可能导致显著的结石生长。这两个修改的证据概述和其他策略,以减少尿草酸排泄进行审查。
Dietary modifications should be considered as a first line approach in the treatment of idiopathic calcium oxalate nephrolithiasis. The amounts of oxalate and calcium consumed in the diet are significant factors in the development of the disease due to their impact on urinary oxalate excretion. There are a number of strategies that can be employed to reduce oxalate excretion. The consumption of oxalate-rich foods should be avoided and calcium intake adjusted to 1000–1200 mg/day. To encourage compliance it should be emphasized to patients that they be vigilant with this diet as a deviation in any meal or snack could potentially result in significant stone growth. The evidence underlying these two modifications is outlined and other strategies to reduce urinary oxalate excretion are reviewed.
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