Comparison of tamsulosin efficacy in subgroups of patients with lower urinary tract symptoms
Comparison of tamsulosin efficacy in subgroups of patients with lower urinary tract symptoms
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坦索罗辛在下尿路症状患者亚组中的疗效比较
DOI：
10.1038/sj.pcan.4500267
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发表时间：
1998
影响因子：
4.8
通讯作者：
M. Goepel
中科院分区：
文献类型：
--
作者：
M. Michel;L. Mehlburger;H. Bressel;M. Goepel
基于两项大规模、开放标签、观察性研究，我们比较了坦索罗辛（0.4 mg，每日一次）在提示良性前列腺梗阻的下尿路症状患者亚组中的治疗结果。IPSS或Qmax的改善基本上不受患者年龄的影响。症状严重的患者从治疗中获益至少与轻度或中度症状的患者一样多，大多数症状严重的患者被转移到中度甚至轻度症状组。我们的结论是，坦索罗辛是有效的，在所有年龄组的患者，并应被视为一种替代手术，即使在患者的严重症状。
We have compared the results of treatment with tamsulosin (0.4 mg once daily) in subgroups of patients with lower urinary tract symptoms suggestive of benign prostatic obstruction, based on two large-scale, open-label, observational studies. Improvements of IPSS or Qmax were largely unaffected by patient age. Patients with severe symptoms benefited at least as much from treatment as those with mild or moderate symptoms, and the majority of patients with severe symptoms were shifted to the moderate or even mild symptoms group. We conclude that tamsulosin is effective in patients of all age groups, and should be considered as an alternative to surgery even in patients with severe symptoms.
影响因子：
6.6
作者：
BARRY, MJ;WILLIFORD, WO;LEPOR, H
通讯作者：
LEPOR, H