The relationship between early childhood blood lead levels and performance on end-of-grade tests.
The relationship between early childhood blood lead levels and performance on end-of-grade tests.
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DOI：
10.1289/ehp.9994
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发表时间：
2007-08
影响因子：
10.4
通讯作者：
Morgan SP
中科院分区：
文献类型：
--
作者：
Miranda ML;Kim D;Galeano MA;Paul CJ;Hull AP;Morgan SP
儿童铅中毒仍然是一个关键的环境健康问题。低水平铅暴露已与学龄儿童标准化智商测试成绩下降有关。
在这项研究中，我们试图确定幼儿期的血铅水平是否与小学低年级的学业成绩相关，学业成绩通过年级末（EOG）测试成绩来衡量。
来自2000 - 2004年北卡罗来纳教育研究数据中心的四年级学生的教育测试数据与北卡罗来纳州七个县的血铅监测数据相关联，然后使用探索性和多元统计方法进行分析。
对于幼儿期低至2微克/分升的血铅水平，血铅水平对EOG测试的明显影响得到了证实。5微克/分升的血铅水平与EOG阅读（和数学）分数的下降有关，这种下降大致相当于四分位距的15%（14%），与通常被认为对教育成果有深远影响的协变量的影响相比，这种影响非常显著。幼儿期铅暴露似乎对测试中的阅读部分成绩的影响比对数学部分的影响更大。
我们强调对年龄大致相同的儿童进行群体水平分析，将其与先前（而非同期）的血铅水平相关联，并使用成绩（而非能力倾向）结果，这对先前研究人员在该领域的重要工作是一种补充。我们的研究结果表明，血铅水平与认知结果之间的关系在不同的结果测量中以及在低水平铅暴露情况下都是稳健的。
Childhood lead poisoning remains a critical environmental health concern. Low-level lead exposure has been linked to decreased performance on standardized IQ tests for school-aged children. In this study we sought to determine whether blood lead levels in early childhood are related to educational achievement in early elementary school as measured by performance on end-of-grade (EOG) testing. Educational testing data for 4th-grade students from the 2000–2004 North Carolina Education Research Data Center were linked to blood lead surveillance data for seven counties in North Carolina and then analyzed using exploratory and multivariate statistical methods. The discernible impact of blood lead levels on EOG testing is demonstrated for early childhood blood lead levels as low as 2 μg/dL. A blood lead level of 5 μg/dL is associated with a decline in EOG reading (and mathematics) scores that is roughly equal to 15% (14%) of the interquartile range, and this impact is very significant in comparison with the effects of covariates typically considered profoundly influential on educational outcomes. Early childhood lead exposures appear to have more impact on performance on the reading than on the mathematics portions of the tests. Our emphasis on population-level analyses of children who are roughly the same age linked to previous (rather than contemporaneous) blood lead levels using achievement (rather than aptitude) outcome complements the important work in this area by previous researchers. Our results suggest that the relationship between blood lead levels and cognitive outcomes are robust across outcome measures and at low levels of lead exposure.
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影响因子：
10.4
作者：
通讯作者：
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影响因子：
158.5
作者：
Canfield, RL;Henderson, CR;Lanphear, BP
通讯作者：
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2.9
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DIETRICH, KN;BERGER, OG;BORNSCHEIN, RL
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影响因子：
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通讯作者：
SCHWARTZ, J
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3.6
作者：
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通讯作者：
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