Prevalence of nosocomial infections and anti-infective therapy in Benin: results of the first nationwide survey in 2012.
Prevalence of nosocomial infections and anti-infective therapy in Benin: results of the first nationwide survey in 2012.
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DOI：
10.1186/2047-2994-3-17
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发表时间：
2014
影响因子：
5.5
通讯作者：
Pittet D
中科院分区：
文献类型：
--
作者：
Ahoyo TA;Bankolé HS;Adéoti FM;Gbohoun AA;Assavèdo S;Amoussou-Guénou M;Kindé-Gazard DA;Pittet D
有关低收入国家医院内感染的数据很少，而且往往不一致。本研究的目的是估计贝宁医院医院感染的流行率和抗菌药物的使用情况。所有医院均受邀参加 2012 年 10 月 10 日至 26 日期间进行的首次全国点流行率研究，该研究采用“欧洲医院通过监测进行感染控制链接”(HELICS) 项目制定的方案。评估了感染流行率、感染患者的比例以及抗菌药物的暴露情况。总体而言，87% (39/45) 的医院参与了。在接受调查的 3130 名住院患者中，597 名患者中发现 972 例院内感染，感染患者总体患病率为 19.1%。最常见的感染与尿路（48.2%）、血管导管的使用（34.7%）和手术部位（24.7%）有关。 64.6%的受访患者接受了抗生素治疗，其中非感染患者比例很高（30%），自我用药比例很高（40.8%）。院内主要病原体对抗菌药物的耐药性包括金黄色葡萄球菌对甲氧西林耐药（52.5%）、肠球菌对万古霉素耐药（67.5%）、大肠杆菌对头孢噻肟耐药（67.6%）、鲍曼不动杆菌和铜绿假单胞菌对头孢他啶耐药（100%） （68.2%）。贝宁院内感染率较高，呼吁实施新的国家感染控制政策。对参与医疗保健服务的所有人员进行患者安全教育和培训对于强调疾病负担的认识至关重要。抗菌药物的大量使用需要解决，特别是在非感染患者中滥用抗菌药物的问题。
Data on nosocomial infections in hospitals in low-income countries are scarce and often inconsistent. The objectives of this study were to estimate the prevalence of nosocomial infections and antimicrobial drug use in Benin hospitals. All hospitals were invited to participate in the first national point prevalence study conducted between 10–26 October 2012 using the protocol developed by the “Hospitals in Europe Link for Infection Control through Surveillance” (HELICS) project. Infection prevalence rates and the proportion of infected patients and exposure to antimicrobials were assessed. Overall, 87% (39/45) of hospitals participated. Of 3130 inpatients surveyed, 972 nosocomial infections were identified among 597 patients, representing an overall prevalence of infected patients of 19.1%. The most frequent infections were related to the urinary tract (48.2%), vascular catheter use (34.7%), and surgical site (24.7%). 64.6% of patients surveyed were treated with antibiotics, including a significant proportion (30%) of non-infected patients and a high proportion of self-medication (40.8%). Resistance of leading nosocomial pathogens to antimicrobials included methicillin-resistance (52.5%) among Staphylococcus aureus, vancomycin resistance among enterococci (67.5%), cefotaxime resistance among Escherichia coli (67.6%), and ceftazidime resistance among Acinetobacter baumannii (100%) and Pseudomonas aeruginosa (68.2%). Benin has high nosocomial infection rates and calls for the implementation of new national infection control policies. Patient safety education and training of all individuals involved in healthcare delivery will be critical to highlight awareness of the burden of disease. The high use of antimicrobials needs to be addressed, particularly their indiscriminate use in non-infected patients.
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影响因子：
168.9
作者：
Allegranzi, Benedetta;Nejad, Sepideh Bagheri;Pittet, Didier
通讯作者：
Pittet, Didier
影响因子：
5
作者：
Ahoyo, A. T.;Baba-Moussa, L.;Dramane, K.
通讯作者：
Dramane, K.
影响因子：
1.8
作者：
Ahoyo, A. -T.;Baba-Moussa, L.;Prevost, G.
通讯作者：
Prevost, G.
影响因子：
4.9
作者：
Cardo, D;Horan, T;Wagner, D
通讯作者：
Wagner, D
影响因子：
9.4
作者：
Kampf, G;Lecke, C;Rüden, H
通讯作者：
Rüden, H