Knowledge Representation for Multi-Scale Physiology Route Modeling.

Knowledge Representation for Multi-Scale Physiology Route Modeling.
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DOI:
10.3389/fninf.2021.560050
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发表时间:
2021
影响因子:
3.5
通讯作者:
de Bono B
de Bono B
中科院分区:
医学3区
文献类型:
--
作者:
Kokash N;de Bono B

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我们提出了一个多尺度生理学路线图的拓扑和语义组装框架。该框架,称为ApiNATOMY,由一个知识表示(KR)模型和一套知识管理(KM)工具。使用ApiNATOMY路线图的例子,我们提出了一个KR格式,适合于分析和可视化的KM工具。概念KR模型为生理学专家提供了一种简单的方法来捕获解剖实体之间的过程相互作用。在本文中,我们概述了KR模型,建模格式,和知识管理程序,以简洁的抽象为基础的规范转换为充分实例化的生理过程模型。
We present a framework for the topological and semantic assembly of multiscale physiology route maps. The framework, called ApiNATOMY, consists of a knowledge representation (KR) model and a set of knowledge management (KM) tools. Using examples of ApiNATOMY route maps, we present a KR format that is suitable for the analysis and visualization by KM tools. The conceptual KR model provides a simple method for physiology experts to capture process interactions among anatomical entities. In this paper, we outline the KR model, modeling format, and the KM procedures to translate concise abstraction-based specifications into fully instantiated models of physiology processes.
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