Automated analysis of pharyngeal pressure data obtained with high-resolution manometry.
Automated analysis of pharyngeal pressure data obtained with high-resolution manometry.
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DOI：
10.1007/s00455-010-9320-2
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发表时间：
2011-03
期刊：
影响因子：
2.6
通讯作者：
McCulloch, Timothy M.
中科院分区：
文献类型：
--
作者：
Mielens, Jason D.;Hoffman, Matthew R.;Ciucci, Michelle R.;Jiang, Jack J.;McCulloch, Timothy M.
关键词：
我们提出了一种在 MATLAB 中开发的算法，该算法可应用于正常和紊乱的吞咽，以从咽部吞咽高分辨率测压 (HRM) 生成的时空图中自动提取各种测量值。该算法是根据 12 名正常受试者和 3 名精神障碍受试者吞咽 5 毫升水丸的数据开发的。将自动提取与手动提取对七个正常受试者和三个紊乱受试者的子集进行比较，以评估算法的准确性。还测量了上食管括约肌开放期间的面积和线积分、压力波速度和压力梯度。自动提取与手动提取显示出很强的相关性，在正常和紊乱受试者中最大腭咽压力和最大舌根压力均产生高相关系数。时间数据也与所有变量密切相关，包括腭咽压力持续时间、舌根压力持续时间和总吞咽持续时间。提供了面积和线积分的初步描述性数据。我们的结果表明该算法可以有效地从 HRM 时空图中自动提取数据。该算法的效率使其成为补充 HRM 临床和研究用途的宝贵工具。
We present an algorithm developed in MATLAB which can be applied to both normal and disordered swallowing to automatically extract a wide array of measurements from the spatiotemporal plots produced by high resolution manometry (HRM) of the pharyngeal swallow. The algorithm was developed from data from twelve normal and three disordered subjects swallowing 5 ml water boluses. Automated extraction was compared to manual extraction for a subset of seven normal and the three disordered subjects to evaluate algorithm accuracy. Area and line integrals, pressure wave velocity, and pressure gradients during upper esophageal sphincter opening were also measured. Automated extraction showed strong correlations with manual extraction, producing high correlation coefficients in both normal and disordered subjects for maximum velopharyngeal pressure and maximum tongue base pressure. Timing data were also strongly correlated for all variables, including velopharyngeal pressure duration, tongue base pressure duration, and total swallow duration. Preliminary descriptive data on area and line integrals are presented. Our results indicate that the algorithm can effectively extract data automatically from HRM spatiotemporal plots. The efficiency of the algorithm makes it a valuable tool to supplement clinical and research use of HRM.
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DOI：
10.1177/000348941011900602
发表时间：
2010-06
期刊：
The Annals of otology, rhinology, and laryngology
影响因子：
--
作者：
McCulloch TM;Hoffman MR;Ciucci MR
通讯作者：
Ciucci MR
影响因子：
4.3
作者：
Hind, JA;Nicosia, MA;Robbins, J
通讯作者：
Robbins, J
影响因子：
2.6
作者：
MCCONNEL, FMS;HOOD, D;OCONNOR, A
通讯作者：
OCONNOR, A
影响因子：
1
作者：
Lazarus, C;Logemann, JA;Kahrilas, PJ
通讯作者：
Kahrilas, PJ
影响因子：
2.6
作者：
Bülow, M;Olsson, R;Ekberg, O
通讯作者：
Ekberg, O